Chronic autoimmune disease characterized by inflammation in multiple organ systems
Drug-induced lupus: uncommon complication of several commonly used medications
Characterized by development of SLE-like symptoms, ANA positivity
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
MR Findings
Ultrasonographic Findings
DEXA Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
Criteria for Classification of SLE (ACRheum)
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Kirchgesner T et al: Instability of the extensor digitorum tendons in Jaccoud arthropathy assessed by semi-dynamic MRI of the metacarpophalangeal joints. Diagn Interv Imaging. 102(9):553-9, 2021
Mahmoud K et al: Ultrasound to identify SLE patients with musculoskeletal symptoms who respond best to therapy: the USEFUL longitudinal multicentre study. Rheumatology (Oxford). 60(11):5194-204, 2021
Zayat AS et al: Defining inflammatory musculoskeletal manifestations in systemic lupus erythematosus. Rheumatology (Oxford). 58(2):304-12, 2019
Tani C et al: Imaging of joints in systemic lupus erythematosus. Clin Exp Rheumatol. 36 Suppl 114(5):68-73, 2018
Ceccarelli F et al: Joint involvement in systemic lupus erythematosus: from pathogenesis to clinical assessment. Semin Arthritis Rheum. 47(1):53-64, 2017
Zayat AS et al: The role of ultrasound in assessing musculoskeletal symptoms of systemic lupus erythematosus: a systematic literature review. Rheumatology (Oxford). 55(3):485-94, 2016
Chiara T et al: MRI pattern of arthritis in systemic lupus erythematosus: a comparative study with rheumatoid arthritis and healthy subjects. Skeletal Radiol. 44(2):261-6, 2015
Edens C et al: Systemic lupus erythematosus, bone health, and osteoporosis. Curr Opin Endocrinol Diabetes Obes. 22(6):422-31, 2015
Lins CF et al: Ultrasound evaluation of joints in systemic lupus erythematosus: a systematic review. Eur Radiol. 25(9):2688-92, 2015
Nakamura J et al: Age at time of corticosteroid administration is a risk factor for osteonecrosis in pediatric patients with systemic lupus erythematosus: a prospective magnetic resonance imaging study. Arthritis Rheum. 62(2):609-15, 2010
Kitaori T et al: Severe erosive arthropathy requiring surgical treatments in systemic lupus erythematosus. Mod Rheumatol. 19(4):431-6, 2009
O'Neill SG et al: Cardiac magnetic resonance imaging in patients with systemic lupus erythematosus. Ann Rheum Dis. 68(9):1478-81, 2009
Schulze M et al: MRI findings in inflammatory muscle diseases and their noninflammatory mimics. AJR Am J Roentgenol. 192(6):1708-16, 2009
Zakavi SR et al: Significance of abnormal myocardial perfusion scintigraphy in young adult patients with SLE. Ann Nucl Med. 23(8):725-8, 2009
Petri M et al: Brain magnetic resonance imaging in newly diagnosed systemic lupus erythematosus. J Rheumatol. 35(12):2348-54, 2008
Martinez JB et al: Erosive arthropathy: clinical variance in lupus erythematosus and association with anti-CCP case series and review of the literature. Clin Exp Rheumatol. 25(1):47-53, 2007
Saketkoo LA et al: Revisiting Jaccoud arthropathy as an ultrasound diagnosed erosive arthropathy in systemic lupus erythematosus. J Clin Rheumatol. 13(6):322-7, 2007
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Systemic lupus erythematosus (SLE)
Synonyms
Lupus, lupus erythematosus
Definitions
Chronic autoimmune disease characterized by inflammation in multiple organ systems
Drug-induced lupus: uncommon complication of several commonly used medications
Characterized by development of SLE-like symptoms, ANA positivity
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
MR Findings
Ultrasonographic Findings
DEXA Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
Criteria for Classification of SLE (ACRheum)
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Kirchgesner T et al: Instability of the extensor digitorum tendons in Jaccoud arthropathy assessed by semi-dynamic MRI of the metacarpophalangeal joints. Diagn Interv Imaging. 102(9):553-9, 2021
Mahmoud K et al: Ultrasound to identify SLE patients with musculoskeletal symptoms who respond best to therapy: the USEFUL longitudinal multicentre study. Rheumatology (Oxford). 60(11):5194-204, 2021
Zayat AS et al: Defining inflammatory musculoskeletal manifestations in systemic lupus erythematosus. Rheumatology (Oxford). 58(2):304-12, 2019
Tani C et al: Imaging of joints in systemic lupus erythematosus. Clin Exp Rheumatol. 36 Suppl 114(5):68-73, 2018
Ceccarelli F et al: Joint involvement in systemic lupus erythematosus: from pathogenesis to clinical assessment. Semin Arthritis Rheum. 47(1):53-64, 2017
Zayat AS et al: The role of ultrasound in assessing musculoskeletal symptoms of systemic lupus erythematosus: a systematic literature review. Rheumatology (Oxford). 55(3):485-94, 2016
Chiara T et al: MRI pattern of arthritis in systemic lupus erythematosus: a comparative study with rheumatoid arthritis and healthy subjects. Skeletal Radiol. 44(2):261-6, 2015
Edens C et al: Systemic lupus erythematosus, bone health, and osteoporosis. Curr Opin Endocrinol Diabetes Obes. 22(6):422-31, 2015
Lins CF et al: Ultrasound evaluation of joints in systemic lupus erythematosus: a systematic review. Eur Radiol. 25(9):2688-92, 2015
Nakamura J et al: Age at time of corticosteroid administration is a risk factor for osteonecrosis in pediatric patients with systemic lupus erythematosus: a prospective magnetic resonance imaging study. Arthritis Rheum. 62(2):609-15, 2010
Kitaori T et al: Severe erosive arthropathy requiring surgical treatments in systemic lupus erythematosus. Mod Rheumatol. 19(4):431-6, 2009
O'Neill SG et al: Cardiac magnetic resonance imaging in patients with systemic lupus erythematosus. Ann Rheum Dis. 68(9):1478-81, 2009
Schulze M et al: MRI findings in inflammatory muscle diseases and their noninflammatory mimics. AJR Am J Roentgenol. 192(6):1708-16, 2009
Zakavi SR et al: Significance of abnormal myocardial perfusion scintigraphy in young adult patients with SLE. Ann Nucl Med. 23(8):725-8, 2009
Petri M et al: Brain magnetic resonance imaging in newly diagnosed systemic lupus erythematosus. J Rheumatol. 35(12):2348-54, 2008
Martinez JB et al: Erosive arthropathy: clinical variance in lupus erythematosus and association with anti-CCP case series and review of the literature. Clin Exp Rheumatol. 25(1):47-53, 2007
Saketkoo LA et al: Revisiting Jaccoud arthropathy as an ultrasound diagnosed erosive arthropathy in systemic lupus erythematosus. J Clin Rheumatol. 13(6):322-7, 2007
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