Intravenous talcosis = talc granulomatosis or excipient lung disease
Definitions
4 forms: 3 inhalational, 1 intravenous
Inhalational talcosis (pure talc exposure)
Inhalational talcosilicosis (exposure to talc and silica)
Inhalational talcoasbestosis (exposure to talc and asbestos)
Intravenous talcosis
Pure intravenous talcosis
Intravenous talcosis and methylphenidate
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Nguyen VT et al: Pulmonary effects of i.v. injection of crushed oral tablets: "excipient lung disease". AJR Am J Roentgenol. 203(5):W506-15, 2014
Marchiori E et al: Pulmonary talcosis: imaging findings. Lung. 188(2):165-71, 2010
van Huisstede A et al: Talcosis due to abundant use of cosmetic talcum powder. Eur Respir Rev. 19(116):165-8, 2010
Akira M et al: Inhalational talc pneumoconiosis: radiographic and CT findings in 14 patients. AJR Am J Roentgenol. 188(2):326-33, 2007
Chong S et al: Pneumoconiosis: comparison of imaging and pathologic findings. Radiographics. 26(1):59-77, 2006
Dekel Y et al: Talc inhalation is a life-threatening condition. Pathol Oncol Res. 10(4):231-3, 2004
Ward S et al: Talcosis associated with IV abuse of oral medications: CT findings. AJR Am J Roentgenol. 174(3):789-93, 2000
Stern EJ et al: Panlobular pulmonary emphysema caused by i.v. injection of methylphenidate (Ritalin): findings on chest radiographs and CT scans. AJR Am J Roentgenol. 162(3):555-60, 1994
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KEY FACTS
Terminology
Imaging
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TERMINOLOGY
Synonyms
Inhalational talcosis = talc pneumoconiosis
Intravenous talcosis = talc granulomatosis or excipient lung disease
Definitions
4 forms: 3 inhalational, 1 intravenous
Inhalational talcosis (pure talc exposure)
Inhalational talcosilicosis (exposure to talc and silica)
Inhalational talcoasbestosis (exposure to talc and asbestos)
Intravenous talcosis
Pure intravenous talcosis
Intravenous talcosis and methylphenidate
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Nguyen VT et al: Pulmonary effects of i.v. injection of crushed oral tablets: "excipient lung disease". AJR Am J Roentgenol. 203(5):W506-15, 2014
Marchiori E et al: Pulmonary talcosis: imaging findings. Lung. 188(2):165-71, 2010
van Huisstede A et al: Talcosis due to abundant use of cosmetic talcum powder. Eur Respir Rev. 19(116):165-8, 2010
Akira M et al: Inhalational talc pneumoconiosis: radiographic and CT findings in 14 patients. AJR Am J Roentgenol. 188(2):326-33, 2007
Chong S et al: Pneumoconiosis: comparison of imaging and pathologic findings. Radiographics. 26(1):59-77, 2006
Dekel Y et al: Talc inhalation is a life-threatening condition. Pathol Oncol Res. 10(4):231-3, 2004
Ward S et al: Talcosis associated with IV abuse of oral medications: CT findings. AJR Am J Roentgenol. 174(3):789-93, 2000
Stern EJ et al: Panlobular pulmonary emphysema caused by i.v. injection of methylphenidate (Ritalin): findings on chest radiographs and CT scans. AJR Am J Roentgenol. 162(3):555-60, 1994
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