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Telangiectatic Osteosarcoma
Behrang Amini, MD, PhD; B. J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Clinical Issues

        • Diagnostic Checklist

          TERMINOLOGY

          • Abbreviations

            • Telangiectatic osteosarcoma (TOS)
          • Definitions

            • Malignant, bone-forming tumor containing cystic or blood-filled spaces separated by fibrous septa

          IMAGING

          • General Features

            • Imaging Recommendations

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      Selected References

                                      1. Amini B et al: Osteoid tumors of bone. Semin Ultrasound CT MR. 42(2):134-49, 2021
                                      2. Baumhoer D et al. Osteosarcoma. In Fletcher CDM et al: WHO Classification of Tumours: Tumours of Soft Tissue and Bone. IARC Press. 403-9, 2020
                                      3. Yarmish G et al: Imaging characteristics of primary osteosarcoma: nonconventional subtypes. Radiographics. 30(6):1653-72, 2010
                                      4. Discepola F et al: Telangiectatic osteosarcoma: radiologic and pathologic findings. Radiographics. 29(2):380-3, 2009
                                      5. Weiss A et al: Telangiectatic osteosarcoma: the St. Jude Children's Research Hospital's experience. Cancer. 109(8):1627-37, 2007
                                      6. Okada K et al: Dedifferentiated chondrosarcoma with telangiectatic osteosarcoma-like features. J Clin Pathol. 59(11):1200-2, 2006
                                      7. Saito T et al: Five-year evolution of a telangiectatic osteosarcoma initially managed as an aneurysmal bone cyst. Skeletal Radiol. 34(5):290-4, 2005
                                      8. Sirikulchayanonta V et al: Soft tissue telangiectatic osteosarcoma in a young patient: imaging and immunostains. Skeletal Radiol. 34(5):295-8, 2005
                                      9. Murphey MD et al: Telangiectatic osteosarcoma: radiologic-pathologic comparison. Radiology. 229(2):545-53, 2003
                                      10. Murphey MD et al: The many faces of osteosarcoma. Radiographics. 17(5):1205-31, 1997
                                      11. Pignatti G et al: Telangiectatic osteogenic sarcoma of the extremities. Results in 17 patients treated with neoadjuvant chemotherapy. Clin Orthop Relat Res. (270):99-106, 1991
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Clinical Issues

                                            • Diagnostic Checklist

                                              TERMINOLOGY

                                              • Abbreviations

                                                • Telangiectatic osteosarcoma (TOS)
                                              • Definitions

                                                • Malignant, bone-forming tumor containing cystic or blood-filled spaces separated by fibrous septa

                                              IMAGING

                                              • General Features

                                                • Imaging Recommendations

                                                  • Radiographic Findings

                                                    • CT Findings

                                                      • MR Findings

                                                        • Nuclear Medicine Findings

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • Gross Pathologic & Surgical Features

                                                              • Microscopic Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Demographics

                                                                    • Natural History & Prognosis

                                                                      • Treatment

                                                                        DIAGNOSTIC CHECKLIST

                                                                        • Consider

                                                                          Selected References

                                                                          1. Amini B et al: Osteoid tumors of bone. Semin Ultrasound CT MR. 42(2):134-49, 2021
                                                                          2. Baumhoer D et al. Osteosarcoma. In Fletcher CDM et al: WHO Classification of Tumours: Tumours of Soft Tissue and Bone. IARC Press. 403-9, 2020
                                                                          3. Yarmish G et al: Imaging characteristics of primary osteosarcoma: nonconventional subtypes. Radiographics. 30(6):1653-72, 2010
                                                                          4. Discepola F et al: Telangiectatic osteosarcoma: radiologic and pathologic findings. Radiographics. 29(2):380-3, 2009
                                                                          5. Weiss A et al: Telangiectatic osteosarcoma: the St. Jude Children's Research Hospital's experience. Cancer. 109(8):1627-37, 2007
                                                                          6. Okada K et al: Dedifferentiated chondrosarcoma with telangiectatic osteosarcoma-like features. J Clin Pathol. 59(11):1200-2, 2006
                                                                          7. Saito T et al: Five-year evolution of a telangiectatic osteosarcoma initially managed as an aneurysmal bone cyst. Skeletal Radiol. 34(5):290-4, 2005
                                                                          8. Sirikulchayanonta V et al: Soft tissue telangiectatic osteosarcoma in a young patient: imaging and immunostains. Skeletal Radiol. 34(5):295-8, 2005
                                                                          9. Murphey MD et al: Telangiectatic osteosarcoma: radiologic-pathologic comparison. Radiology. 229(2):545-53, 2003
                                                                          10. Murphey MD et al: The many faces of osteosarcoma. Radiographics. 17(5):1205-31, 1997
                                                                          11. Pignatti G et al: Telangiectatic osteogenic sarcoma of the extremities. Results in 17 patients treated with neoadjuvant chemotherapy. Clin Orthop Relat Res. (270):99-106, 1991