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Temporal Bone Paget Disease
H. Ric Harnsberger, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Abbreviations

            • Paget disease (PD)
          • Synonyms

            • Osteitis deformans
          • Definitions

            • Bone dysplasia characterized by excessive remodeling of bone resulting from alternating waves of osteoclastic & osteoblastic activity

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Microscopic Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  Selected References

                                  1. Bahmad F Jr et al: Paget disease of the temporal bone. Otol Neurotol. 28(8):1157-8, 2007
                                  2. Teufert KB et al: Paget disease and sensorineural hearing loss associated with spiral ligament degeneration. Otol Neurotol. 26(3):387-91; discussion 391, 2005
                                  3. Van der Stappen A et al: Paget disease of the skull and temporal bone. JBR-BTR. 88(3):156-7, 2005
                                  4. Donáth J et al: Effect of bisphosphonate treatment in patients with Paget's disease of the skull. Rheumatology (Oxford). 43(1):89-94, 2004
                                  5. Tehranzadeh J et al: Computed tomography of Paget disease of the skull versus fibrous dysplasia. Skeletal Radiol. 27(12):664-72, 1998
                                  6. Monsell EM et al: Hearing loss in Paget's disease of bone: evidence of auditory nerve integrity. Am J Otol. 16(1):27-33, 1995
                                  7. Ramsay HA et al: Cochlear histopathology in Paget's disease. Am J Otolaryngol. 14(1):60-1, 1993
                                  8. d'Archambeau O et al: CT diagnosis and differential diagnosis of otodystrophic lesions of the temporal bone. Eur J Radiol. 11(1):22-30, 1990
                                  9. Khetarpal U et al: In search of pathologic correlates for hearing loss and vertigo in Paget's disease. A clinical and histopathologic study of 26 temporal bones. Ann Otol Rhinol Laryngol Suppl. 145:1-16, 1990
                                  Related Anatomy
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                                  Related Differential Diagnoses
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                                  References
                                  Tables

                                  Tables

                                  KEY FACTS

                                  • Terminology

                                    • Imaging

                                      • Top Differential Diagnoses

                                        • Clinical Issues

                                          TERMINOLOGY

                                          • Abbreviations

                                            • Paget disease (PD)
                                          • Synonyms

                                            • Osteitis deformans
                                          • Definitions

                                            • Bone dysplasia characterized by excessive remodeling of bone resulting from alternating waves of osteoclastic & osteoblastic activity

                                          IMAGING

                                          • General Features

                                            • Radiographic Findings

                                              • CT Findings

                                                • MR Findings

                                                  • Imaging Recommendations

                                                    DIFFERENTIAL DIAGNOSIS

                                                      PATHOLOGY

                                                      • General Features

                                                        • Microscopic Features

                                                          CLINICAL ISSUES

                                                          • Presentation

                                                            • Demographics

                                                              • Natural History & Prognosis

                                                                • Treatment

                                                                  Selected References

                                                                  1. Bahmad F Jr et al: Paget disease of the temporal bone. Otol Neurotol. 28(8):1157-8, 2007
                                                                  2. Teufert KB et al: Paget disease and sensorineural hearing loss associated with spiral ligament degeneration. Otol Neurotol. 26(3):387-91; discussion 391, 2005
                                                                  3. Van der Stappen A et al: Paget disease of the skull and temporal bone. JBR-BTR. 88(3):156-7, 2005
                                                                  4. Donáth J et al: Effect of bisphosphonate treatment in patients with Paget's disease of the skull. Rheumatology (Oxford). 43(1):89-94, 2004
                                                                  5. Tehranzadeh J et al: Computed tomography of Paget disease of the skull versus fibrous dysplasia. Skeletal Radiol. 27(12):664-72, 1998
                                                                  6. Monsell EM et al: Hearing loss in Paget's disease of bone: evidence of auditory nerve integrity. Am J Otol. 16(1):27-33, 1995
                                                                  7. Ramsay HA et al: Cochlear histopathology in Paget's disease. Am J Otolaryngol. 14(1):60-1, 1993
                                                                  8. d'Archambeau O et al: CT diagnosis and differential diagnosis of otodystrophic lesions of the temporal bone. Eur J Radiol. 11(1):22-30, 1990
                                                                  9. Khetarpal U et al: In search of pathologic correlates for hearing loss and vertigo in Paget's disease. A clinical and histopathologic study of 26 temporal bones. Ann Otol Rhinol Laryngol Suppl. 145:1-16, 1990