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Head and Neck
Diagnosis
Temporal Bone
Middle Ear-Mastoid
Benign and Malignant Tumors
Temporal Bone Rhabdomyosarcoma
Temporal Bone Rhabdomyosarcoma
Hilda E. Stambuk, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Abbreviations

            • Rhabdomyosarcoma (RMS)

          • Definitions

            • Rare, destructive, pediatric T-bone lesion
              • Arises from embryonic skeletal muscle precursor cells or pluripotential mesenchymal cells

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Nuclear Medicine Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          • Reporting Tips

                                            Selected References

                                            1. Do TN et al: Cranial rhabdomyosarcoma masquerading as infectious mastoiditis: case report and literature review. Pediatr Neurosurg. 53(5):317-21, 2018
                                            2. Chevallier KM et al: Differentiating pediatric rhabdomyosarcoma and Langerhans cell histiocytosis of the temporal bone by imaging appearance. AJNR Am J Neuroradiol. 37(6):1185-9, 2016
                                            3. Goldberg MJ: Pediatric temporal bone rhabdomyosarcoma. JAAPA. 29(8):1-3, 2016
                                            4. Gluth MB: Rhabdomyosarcoma and other pediatric temporal bone malignancies. Otolaryngol Clin North Am. 48(2):375-90, 2015
                                            5. Wolden SL et al: Local control for intermediate-risk rhabdomyosarcoma: results from D9803 according to histology, group, site, and size: a report from the Children's Oncology Group. Int J Radiat Oncol Biol Phys. 93(5):1071-6, 2015
                                            6. Gosiengfiao Y et al: What is new in rhabdomyosarcoma management in children? Paediatr Drugs. 14(6):389-400, 2012
                                            7. Turner JH et al: Head and neck rhabdomyosarcoma: a critical analysis of population-based incidence and survival data. Otolaryngol Head Neck Surg. 145(6):967-73, 2011
                                            8. Freling NJ et al: Imaging findings in craniofacial childhood rhabdomyosarcoma. Pediatr Radiol. 40(11):1723-38; quiz 1855, 2010
                                            9. Robson CD: Imaging of head and neck neoplasms in children. Pediatr Radiol. 40(4):499-509, 2010
                                            10. De Foer B et al: Imaging of temporal bone tumors. Neuroimaging Clin N Am. 19(3):339-66, 2009
                                            11. Bisogno G et al: Improved survival for children with parameningeal rhabdomyosarcoma: results from the AIEOP soft tissue sarcoma committee. Pediatr Blood Cancer. 50(6):1154-8, 2008
                                            12. Connor SE et al: Imaging of the petrous apex: a pictorial review. Br J Radiol. 81(965):427-35, 2008
                                            13. Van Rijn RR et al: Imaging findings in noncraniofacial childhood rhabdomyosarcoma. Pediatr Radiol. 38(6):617-34, 2008
                                            14. Sbeity S et al: Temporal bone rhabdomyosarcoma in children. Int J Pediatr Otorhinolaryngol. 71(5):807-14, 2007
                                            15. Viswanatha B: Embryonal rhabdomyosarcoma of the temporal bone. Ear Nose Throat J. 86(4):218, 220-2, 2007
                                            16. Reid SR et al: Temporal bone rhabdomyosarcoma presenting as acute peripheral facial nerve paralysis. Pediatr Emerg Care. 22(10):743-5, 2006
                                            17. Raney RB et al: Rhabdomyosarcoma and undifferentiated sarcoma in the first two decades of life: a selective review of intergroup rhabdomyosarcoma study group experience and rationale for Intergroup Rhabdomyosarcoma Study V. J Pediatr Hematol Oncol. 23(4):215-20, 2001
                                            18. Mena JC et al: Case 3: Temporal bone rhabdomyosarcoma. AJR Am J Roentgenol. 171(3):873, 877-9, 1998
                                            19. Zampa V et al: Rhabdomyosarcoma of the petrous ridge. CT and MR imaging in an atypical case with multiple cranial nerve palsy. Acta Radiol. 33(1):76-8, 1992
                                            20. Wiatrak BJ et al: Rhabdomyosarcoma of the ear and temporal bone. Laryngoscope. 99(11):1188-92, 1989
                                            21. De SK et al: Tumours of the mastoid temporal bone: with interesting cases in the paediatric age group. J Laryngol Otol. 102(7):582-7, 1988
                                            22. Said H et al: Rhabdomyosarcoma of the middle ear and mastoid in children. J Laryngol Otol. 102(7):614-9, 1988
                                            23. Latack JT et al: Imaging of rhabdomyosarcomas of the head and neck. AJNR Am J Neuroradiol. 8(2):353-9, 1987
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Clinical Issues

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Rhabdomyosarcoma (RMS)

                                                    • Definitions

                                                      • Rare, destructive, pediatric T-bone lesion
                                                        • Arises from embryonic skeletal muscle precursor cells or pluripotential mesenchymal cells

                                                    IMAGING

                                                    • General Features

                                                      • CT Findings

                                                        • MR Findings

                                                          • Nuclear Medicine Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Staging, Grading, & Classification

                                                                    • Gross Pathologic & Surgical Features

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Consider

                                                                                  • Image Interpretation Pearls

                                                                                    • Reporting Tips

                                                                                      Selected References

                                                                                      1. Do TN et al: Cranial rhabdomyosarcoma masquerading as infectious mastoiditis: case report and literature review. Pediatr Neurosurg. 53(5):317-21, 2018
                                                                                      2. Chevallier KM et al: Differentiating pediatric rhabdomyosarcoma and Langerhans cell histiocytosis of the temporal bone by imaging appearance. AJNR Am J Neuroradiol. 37(6):1185-9, 2016
                                                                                      3. Goldberg MJ: Pediatric temporal bone rhabdomyosarcoma. JAAPA. 29(8):1-3, 2016
                                                                                      4. Gluth MB: Rhabdomyosarcoma and other pediatric temporal bone malignancies. Otolaryngol Clin North Am. 48(2):375-90, 2015
                                                                                      5. Wolden SL et al: Local control for intermediate-risk rhabdomyosarcoma: results from D9803 according to histology, group, site, and size: a report from the Children's Oncology Group. Int J Radiat Oncol Biol Phys. 93(5):1071-6, 2015
                                                                                      6. Gosiengfiao Y et al: What is new in rhabdomyosarcoma management in children? Paediatr Drugs. 14(6):389-400, 2012
                                                                                      7. Turner JH et al: Head and neck rhabdomyosarcoma: a critical analysis of population-based incidence and survival data. Otolaryngol Head Neck Surg. 145(6):967-73, 2011
                                                                                      8. Freling NJ et al: Imaging findings in craniofacial childhood rhabdomyosarcoma. Pediatr Radiol. 40(11):1723-38; quiz 1855, 2010
                                                                                      9. Robson CD: Imaging of head and neck neoplasms in children. Pediatr Radiol. 40(4):499-509, 2010
                                                                                      10. De Foer B et al: Imaging of temporal bone tumors. Neuroimaging Clin N Am. 19(3):339-66, 2009
                                                                                      11. Bisogno G et al: Improved survival for children with parameningeal rhabdomyosarcoma: results from the AIEOP soft tissue sarcoma committee. Pediatr Blood Cancer. 50(6):1154-8, 2008
                                                                                      12. Connor SE et al: Imaging of the petrous apex: a pictorial review. Br J Radiol. 81(965):427-35, 2008
                                                                                      13. Van Rijn RR et al: Imaging findings in noncraniofacial childhood rhabdomyosarcoma. Pediatr Radiol. 38(6):617-34, 2008
                                                                                      14. Sbeity S et al: Temporal bone rhabdomyosarcoma in children. Int J Pediatr Otorhinolaryngol. 71(5):807-14, 2007
                                                                                      15. Viswanatha B: Embryonal rhabdomyosarcoma of the temporal bone. Ear Nose Throat J. 86(4):218, 220-2, 2007
                                                                                      16. Reid SR et al: Temporal bone rhabdomyosarcoma presenting as acute peripheral facial nerve paralysis. Pediatr Emerg Care. 22(10):743-5, 2006
                                                                                      17. Raney RB et al: Rhabdomyosarcoma and undifferentiated sarcoma in the first two decades of life: a selective review of intergroup rhabdomyosarcoma study group experience and rationale for Intergroup Rhabdomyosarcoma Study V. J Pediatr Hematol Oncol. 23(4):215-20, 2001
                                                                                      18. Mena JC et al: Case 3: Temporal bone rhabdomyosarcoma. AJR Am J Roentgenol. 171(3):873, 877-9, 1998
                                                                                      19. Zampa V et al: Rhabdomyosarcoma of the petrous ridge. CT and MR imaging in an atypical case with multiple cranial nerve palsy. Acta Radiol. 33(1):76-8, 1992
                                                                                      20. Wiatrak BJ et al: Rhabdomyosarcoma of the ear and temporal bone. Laryngoscope. 99(11):1188-92, 1989
                                                                                      21. De SK et al: Tumours of the mastoid temporal bone: with interesting cases in the paediatric age group. J Laryngol Otol. 102(7):582-7, 1988
                                                                                      22. Said H et al: Rhabdomyosarcoma of the middle ear and mastoid in children. J Laryngol Otol. 102(7):614-9, 1988
                                                                                      23. Latack JT et al: Imaging of rhabdomyosarcomas of the head and neck. AJNR Am J Neuroradiol. 8(2):353-9, 1987