Ablation: Percutaneous direct local tumor destruction
Energy-based ablation
Radiofrequency ablation (RFA): Heat based
Aerated lung limits energy deposition
Cryoablation: Freezing/thawing cycle
Can be done closer to pleura and vessels
Microwave ablation: Heat-based cytotoxicity
Less limited by aerated lung than RFA
Risk of bronchopleural fistula along lung periphery
Irreversible electroporation: Electrical disruption of integrity of cell membrane
Embolization: Transcatheter introduction of intravascular agent for devascularization/occlusion
Artificial pneumothorax: Intentional creation of pneumothorax during ablation procedure
Displaces ablation zone away from critical structures
May be needed if tumor adjacent to large vascular structures (e.g., heart) or phrenic nerve
PREPROCEDURE
Indications
Contraindications
Preprocedure Imaging
Getting Started
PROCEDURE
Patient Position/Location
Procedure Steps
Alternative Procedures/Therapies
POST PROCEDURE
Things to Do
Things to Avoid
Postprocedure Imaging (Ablation)
OUTCOMES
Complications
Expected Outcomes
Selected References
Cernic S et al: Percutaneous CT-guided renal cryoablation: technical aspects, safety, and long-term oncological outcomes in a single center. Medicina (Kaunas). 57(3):291, 2021
Cazzato RL et al: Percutaneous image-guided cryoablation: current applications and results in the oncologic field. Med Oncol. 33(12):140, 2016
Zhang YS et al: Percutaneous imaging-guided cryoablation for lung cancer. J Thorac Dis. 8(Suppl 9):S705-9, 2016
Dupuy DE: Image-guided thermal ablation of lung malignancies. Radiology. 260(3):633-55, 2011
Sofocleous CT et al: Ablation for the management of pulmonary malignancies. AJR Am J Roentgenol. 197(4):W581-9, 2011
Vogl TJ et al: Radiofrequency, microwave and laser ablation of pulmonary neoplasms: clinical studies and technical considerations--review article. Eur J Radiol. 77(2):346-57, 2011
Yamauchi Y et al: Percutaneous cryoablation of pulmonary metastases from colorectal cancer. PLoS One. 6(11):e27086, 2011
Beland MD et al: Primary non-small cell lung cancer: review of frequency, location, and time of recurrence after radiofrequency ablation. Radiology. 254(1):301-7, 2010
Pua BB et al: Ablation of pulmonary malignancy: current status. J Vasc Interv Radiol. 21(8 Suppl):S223-32, 2010
Solomon SB et al: Protection of the mediastinum and chest wall with an artificial pneumothorax during lung ablations. J Vasc Interv Radiol. 19(4):610-5, 2008
Bojarski JD et al: CT imaging findings of pulmonary neoplasms after treatment with radiofrequency ablation: results in 32 tumors. AJR Am J Roentgenol. 185(2):466-71, 2005
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Preprocedure
Procedure
Post Procedure
Outcomes
TERMINOLOGY
Definitions
Ablation: Percutaneous direct local tumor destruction
Energy-based ablation
Radiofrequency ablation (RFA): Heat based
Aerated lung limits energy deposition
Cryoablation: Freezing/thawing cycle
Can be done closer to pleura and vessels
Microwave ablation: Heat-based cytotoxicity
Less limited by aerated lung than RFA
Risk of bronchopleural fistula along lung periphery
Irreversible electroporation: Electrical disruption of integrity of cell membrane
Embolization: Transcatheter introduction of intravascular agent for devascularization/occlusion
Artificial pneumothorax: Intentional creation of pneumothorax during ablation procedure
Displaces ablation zone away from critical structures
May be needed if tumor adjacent to large vascular structures (e.g., heart) or phrenic nerve
PREPROCEDURE
Indications
Contraindications
Preprocedure Imaging
Getting Started
PROCEDURE
Patient Position/Location
Procedure Steps
Alternative Procedures/Therapies
POST PROCEDURE
Things to Do
Things to Avoid
Postprocedure Imaging (Ablation)
OUTCOMES
Complications
Expected Outcomes
Selected References
Cernic S et al: Percutaneous CT-guided renal cryoablation: technical aspects, safety, and long-term oncological outcomes in a single center. Medicina (Kaunas). 57(3):291, 2021
Cazzato RL et al: Percutaneous image-guided cryoablation: current applications and results in the oncologic field. Med Oncol. 33(12):140, 2016
Zhang YS et al: Percutaneous imaging-guided cryoablation for lung cancer. J Thorac Dis. 8(Suppl 9):S705-9, 2016
Dupuy DE: Image-guided thermal ablation of lung malignancies. Radiology. 260(3):633-55, 2011
Sofocleous CT et al: Ablation for the management of pulmonary malignancies. AJR Am J Roentgenol. 197(4):W581-9, 2011
Vogl TJ et al: Radiofrequency, microwave and laser ablation of pulmonary neoplasms: clinical studies and technical considerations--review article. Eur J Radiol. 77(2):346-57, 2011
Yamauchi Y et al: Percutaneous cryoablation of pulmonary metastases from colorectal cancer. PLoS One. 6(11):e27086, 2011
Beland MD et al: Primary non-small cell lung cancer: review of frequency, location, and time of recurrence after radiofrequency ablation. Radiology. 254(1):301-7, 2010
Pua BB et al: Ablation of pulmonary malignancy: current status. J Vasc Interv Radiol. 21(8 Suppl):S223-32, 2010
Solomon SB et al: Protection of the mediastinum and chest wall with an artificial pneumothorax during lung ablations. J Vasc Interv Radiol. 19(4):610-5, 2008
Bojarski JD et al: CT imaging findings of pulmonary neoplasms after treatment with radiofrequency ablation: results in 32 tumors. AJR Am J Roentgenol. 185(2):466-71, 2005
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