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Thymic Neuroendocrine Neoplasm
Sherief H. Garrana, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Thymic neuroendocrine neoplasm (TNEN)
                • Thymic carcinoid (TC)
              • Definitions

                • Primary malignant neuroendocrine neoplasm

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Gross Pathologic & Surgical Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Ruffini E et al: The International Association for the Study of Lung Cancer Thymic Tumors staging project: the impact of the eighth edition of the Union for International Cancer Control and American Joint Committee on Cancer TNM Stage Classification of Thymic Tumors. J Thorac Oncol. 15(3):436-447, 2020
                                              2. Hsu CH et al: Trends in the incidence of thymoma, thymic carcinoma, and thymic neuroendocrine tumor in the United States. PLoS One. 14(12):e0227197, 2019
                                              3. Al-Salameh A et al: Update on multiple endocrine neoplasia Type 1 and 2. Presse Med. 47(9):722-31, 2018
                                              4. Araki T et al: Radiological features and metastatic patterns of thymic neuroendocrine tumours. Clin Radiol. 73(5):479-84, 2018
                                              5. Filosso PL et al: Neuroendocrine tumors of the thymus. J Thorac Dis. 9(Suppl 15):S1484-90, 2017
                                              6. Ried M et al: Evaluation of the new TNM-staging system for thymic malignancies: impact on indication and survival. World J Surg Oncol. 15(1):214, 2017
                                              7. Shimamoto A et al: CT and MRI findings of thymic carcinoid. Br J Radiol. 90(1071):20150341, 2017
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Clinical Issues

                                                        • Diagnostic Checklist

                                                          TERMINOLOGY

                                                          • Synonyms

                                                            • Thymic neuroendocrine neoplasm (TNEN)
                                                            • Thymic carcinoid (TC)
                                                          • Definitions

                                                            • Primary malignant neuroendocrine neoplasm

                                                          IMAGING

                                                          • General Features

                                                            • Radiographic Findings

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Nuclear Medicine Findings

                                                                    • Imaging Recommendations

                                                                      DIFFERENTIAL DIAGNOSIS

                                                                        PATHOLOGY

                                                                        • General Features

                                                                          • Staging, Grading, & Classification

                                                                            • Gross Pathologic & Surgical Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Consider

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Ruffini E et al: The International Association for the Study of Lung Cancer Thymic Tumors staging project: the impact of the eighth edition of the Union for International Cancer Control and American Joint Committee on Cancer TNM Stage Classification of Thymic Tumors. J Thorac Oncol. 15(3):436-447, 2020
                                                                                          2. Hsu CH et al: Trends in the incidence of thymoma, thymic carcinoma, and thymic neuroendocrine tumor in the United States. PLoS One. 14(12):e0227197, 2019
                                                                                          3. Al-Salameh A et al: Update on multiple endocrine neoplasia Type 1 and 2. Presse Med. 47(9):722-31, 2018
                                                                                          4. Araki T et al: Radiological features and metastatic patterns of thymic neuroendocrine tumours. Clin Radiol. 73(5):479-84, 2018
                                                                                          5. Filosso PL et al: Neuroendocrine tumors of the thymus. J Thorac Dis. 9(Suppl 15):S1484-90, 2017
                                                                                          6. Ried M et al: Evaluation of the new TNM-staging system for thymic malignancies: impact on indication and survival. World J Surg Oncol. 15(1):214, 2017
                                                                                          7. Shimamoto A et al: CT and MRI findings of thymic carcinoid. Br J Radiol. 90(1071):20150341, 2017