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Thyroglossal Duct Cyst Carcinoma
Luke N. Ledbetter, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Thyroglossal duct carcinoma (TGDCa)
              • Definitions

                • Malignant tumor arising from remnants of embryologic thyroglossal duct (TGD)
                  • Most often occurs within TGD

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Shah S et al: Squamous cell carcinoma in a thyroglossal duct cyst: a case report with review of the literature. Am J Otolaryngol. 36(3):460-2, 2015
                                        2. Wei S et al: Pathology of thyroglossal duct: an institutional experience. Endocr Pathol. 26(1):75-9, 2015
                                        3. Carter Y et al: Thyroglossal duct remnant carcinoma: beyond the Sistrunk procedure. Surg Oncol. 23(3):161-6, 2014
                                        4. Kwon JK et al: Papillary thyroid carcinoma arising from a primary thyroglossal duct cyst with cervical node metastases. Thyroid. 22(3):330-1, 2012
                                        5. Forest VI et al: Thyroglossal duct cyst carcinoma: case series. J Otolaryngol Head Neck Surg. 40(2):151-6, 2011
                                        6. Wang CP et al: F-18 FDG uptake in papillary carcinoma arising from thyroglossal duct cyst. Clin Nucl Med. 36(2):141-2, 2011
                                        7. Kermani W et al: Papillary carcinoma arising in a thyroglossal duct cyst: case report and discussion of management modalities. Eur Arch Otorhinolaryngol. 265(2):233-6, 2008
                                        8. Motamed M et al: Thyroglossal duct carcinoma. Curr Opin Otolaryngol Head Neck Surg. 12(2):106-9, 2004
                                        9. Peretz A et al: Thyroglossal duct carcinoma in children: case presentation and review of the literature. Thyroid. 14(9):777-85, 2004
                                        10. Massine RE et al: Lingual thyroid carcinoma: a case report and review of the literature. Thyroid. 11(12):1191-6, 2001
                                        11. Branstetter BF et al: The CT appearance of thyroglossal duct carcinoma. AJNR Am J Neuroradiol. 21(8):1547-50, 2000
                                        12. Glastonbury CM et al: The CT and MR imaging features of carcinoma arising in thyroglossal duct remnants. AJNR Am J Neuroradiol. 21(4):770-4, 2000
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Thyroglossal duct carcinoma (TGDCa)
                                                    • Definitions

                                                      • Malignant tumor arising from remnants of embryologic thyroglossal duct (TGD)
                                                        • Most often occurs within TGD

                                                    IMAGING

                                                    • General Features

                                                      • CT Findings

                                                        • MR Findings

                                                          • Ultrasonographic Findings

                                                            • Nuclear Medicine Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Treatment

                                                                          DIAGNOSTIC CHECKLIST

                                                                          • Consider

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Shah S et al: Squamous cell carcinoma in a thyroglossal duct cyst: a case report with review of the literature. Am J Otolaryngol. 36(3):460-2, 2015
                                                                              2. Wei S et al: Pathology of thyroglossal duct: an institutional experience. Endocr Pathol. 26(1):75-9, 2015
                                                                              3. Carter Y et al: Thyroglossal duct remnant carcinoma: beyond the Sistrunk procedure. Surg Oncol. 23(3):161-6, 2014
                                                                              4. Kwon JK et al: Papillary thyroid carcinoma arising from a primary thyroglossal duct cyst with cervical node metastases. Thyroid. 22(3):330-1, 2012
                                                                              5. Forest VI et al: Thyroglossal duct cyst carcinoma: case series. J Otolaryngol Head Neck Surg. 40(2):151-6, 2011
                                                                              6. Wang CP et al: F-18 FDG uptake in papillary carcinoma arising from thyroglossal duct cyst. Clin Nucl Med. 36(2):141-2, 2011
                                                                              7. Kermani W et al: Papillary carcinoma arising in a thyroglossal duct cyst: case report and discussion of management modalities. Eur Arch Otorhinolaryngol. 265(2):233-6, 2008
                                                                              8. Motamed M et al: Thyroglossal duct carcinoma. Curr Opin Otolaryngol Head Neck Surg. 12(2):106-9, 2004
                                                                              9. Peretz A et al: Thyroglossal duct carcinoma in children: case presentation and review of the literature. Thyroid. 14(9):777-85, 2004
                                                                              10. Massine RE et al: Lingual thyroid carcinoma: a case report and review of the literature. Thyroid. 11(12):1191-6, 2001
                                                                              11. Branstetter BF et al: The CT appearance of thyroglossal duct carcinoma. AJNR Am J Neuroradiol. 21(8):1547-50, 2000
                                                                              12. Glastonbury CM et al: The CT and MR imaging features of carcinoma arising in thyroglossal duct remnants. AJNR Am J Neuroradiol. 21(4):770-4, 2000