Acute transmural fulminant colitis with neuromuscular degeneration and colonic dilation
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Skomorochow E et al: Toxic megacolon. StatPearls, 2021
Eghbali E et al: CT features of toxic megacolon: a systematic review. Radiography (Lond). 27(2):716-20, 2020
Doshi R et al: Incidence, features, in-hospital outcomes and predictors of in-hospital mortality associated with toxic megacolon hospitalizations in the United States. Intern Emerg Med. 13(6):881-7, 2018
Ong SCL et al: Imaging features of toxic megacolon. BMJ Case Rep. 2018, 2018
Jethwa KD et al: The importance of the abdominal X-radiograph in acute ulcerative colitis. Arch Dis Child Educ Pract Ed. 99(5):188, 200, 2014
Kazanowski M et al: Clostridium difficile: epidemiology, diagnostic and therapeutic possibilities-a systematic review. Tech Coloproctol. 18(3):223-32, 2014
Miniello S et al: Toxic megacolon in ulcerative rectocolitis. Current trends in clinical evaluation, diagnosis and treatment. Ann Ital Chir. 85(1):45-9, 2014
Narabayashi K et al: Oral tacrolimus for megacolon in patients with severe ulcerative colitis. Intern Med. 53(16):1755-8, 2014
Yu S et al: Fecal transplant for treatment of toxic megacolon associated with clostridium difficile colitis in a patient with duchenne muscular dystrophy. Am J Ther. 23(2):e609-13, 2014
Gan SI et al: A new look at toxic megacolon: an update and review of incidence, etiology, pathogenesis, and management. Am J Gastroenterol. 98(11):2363-71, 2003
Latella G et al: GI distension in severe ulcerative colitis. Am J Gastroenterol. 97(5):1169-75, 2002
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KEY FACTS
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TERMINOLOGY
Definitions
Acute transmural fulminant colitis with neuromuscular degeneration and colonic dilation
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Skomorochow E et al: Toxic megacolon. StatPearls, 2021
Eghbali E et al: CT features of toxic megacolon: a systematic review. Radiography (Lond). 27(2):716-20, 2020
Doshi R et al: Incidence, features, in-hospital outcomes and predictors of in-hospital mortality associated with toxic megacolon hospitalizations in the United States. Intern Emerg Med. 13(6):881-7, 2018
Ong SCL et al: Imaging features of toxic megacolon. BMJ Case Rep. 2018, 2018
Jethwa KD et al: The importance of the abdominal X-radiograph in acute ulcerative colitis. Arch Dis Child Educ Pract Ed. 99(5):188, 200, 2014
Kazanowski M et al: Clostridium difficile: epidemiology, diagnostic and therapeutic possibilities-a systematic review. Tech Coloproctol. 18(3):223-32, 2014
Miniello S et al: Toxic megacolon in ulcerative rectocolitis. Current trends in clinical evaluation, diagnosis and treatment. Ann Ital Chir. 85(1):45-9, 2014
Narabayashi K et al: Oral tacrolimus for megacolon in patients with severe ulcerative colitis. Intern Med. 53(16):1755-8, 2014
Yu S et al: Fecal transplant for treatment of toxic megacolon associated with clostridium difficile colitis in a patient with duchenne muscular dystrophy. Am J Ther. 23(2):e609-13, 2014
Gan SI et al: A new look at toxic megacolon: an update and review of incidence, etiology, pathogenesis, and management. Am J Gastroenterol. 98(11):2363-71, 2003
Latella G et al: GI distension in severe ulcerative colitis. Am J Gastroenterol. 97(5):1169-75, 2002
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