John P. Lichtenberger, III, MD; Jeffrey P. Kanne, MD
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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
Airway amyloidosis
Definitions
Focal or diffuse submucosal deposition of amyloid in tracheobronchial tree
Characterized by amyloid light chain (AL) protein
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Bedayat A et al: Tracheobronchial tumors: radiologic-pathologic correlation of tumors and mimics. Curr Probl Diagn Radiol. 49(4):275-84, 2020
Brandelik SC et al: CT features in amyloidosis of the respiratory system - Comprehensive analysis in a tertiary referral center cohort. Eur J Radiol. 129:109123, 2020
Shepard JO et al: Imaging of the trachea. Ann Cardiothorac Surg. 7(2):197-209, 2018
de Almeida RR et al: Respiratory Tract Amyloidosis. State-of-the-Art Review with a Focus on Pulmonary Involvement. Lung. 193(6):875-83, 2015
Chung JH et al: CT of diffuse tracheal diseases. AJR Am J Roentgenol. 196(3):W240-6, 2011
Gilad R et al: Severe diffuse systemic amyloidosis with involvement of the pharynx, larynx, and trachea: CT and MR findings. AJNR Am J Neuroradiol. 28(8):1557-8, 2007
Neben-Wittich MA et al: External beam radiation therapy for tracheobronchial amyloidosis. Chest. 132(1):262-7, 2007
Aylwin AC et al: Imaging appearance of thoracic amyloidosis. J Thorac Imaging. 20(1):41-6, 2005
Dahl KA et al: Tracheobronchial amyloidosis: a surgical disease with long-term consequences. J Thorac Cardiovasc Surg. 128(5):789-92, 2004
Gibbaoui H et al: A case of primary diffuse tracheobronchial amyloidosis. Ann Thorac Surg. 77(5):1832-4, 2004
Toyoda M et al: Tracheobronchial AL amyloidosis: histologic, immunohistochemical, ultrastructural, and immunoelectron microscopic observations. Hum Pathol. 24(9):970-6, 1993
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
Airway amyloidosis
Definitions
Focal or diffuse submucosal deposition of amyloid in tracheobronchial tree
Characterized by amyloid light chain (AL) protein
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Bedayat A et al: Tracheobronchial tumors: radiologic-pathologic correlation of tumors and mimics. Curr Probl Diagn Radiol. 49(4):275-84, 2020
Brandelik SC et al: CT features in amyloidosis of the respiratory system - Comprehensive analysis in a tertiary referral center cohort. Eur J Radiol. 129:109123, 2020
Shepard JO et al: Imaging of the trachea. Ann Cardiothorac Surg. 7(2):197-209, 2018
de Almeida RR et al: Respiratory Tract Amyloidosis. State-of-the-Art Review with a Focus on Pulmonary Involvement. Lung. 193(6):875-83, 2015
Chung JH et al: CT of diffuse tracheal diseases. AJR Am J Roentgenol. 196(3):W240-6, 2011
Gilad R et al: Severe diffuse systemic amyloidosis with involvement of the pharynx, larynx, and trachea: CT and MR findings. AJNR Am J Neuroradiol. 28(8):1557-8, 2007
Neben-Wittich MA et al: External beam radiation therapy for tracheobronchial amyloidosis. Chest. 132(1):262-7, 2007
Aylwin AC et al: Imaging appearance of thoracic amyloidosis. J Thorac Imaging. 20(1):41-6, 2005
Dahl KA et al: Tracheobronchial amyloidosis: a surgical disease with long-term consequences. J Thorac Cardiovasc Surg. 128(5):789-92, 2004
Gibbaoui H et al: A case of primary diffuse tracheobronchial amyloidosis. Ann Thorac Surg. 77(5):1832-4, 2004
Toyoda M et al: Tracheobronchial AL amyloidosis: histologic, immunohistochemical, ultrastructural, and immunoelectron microscopic observations. Hum Pathol. 24(9):970-6, 1993
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