Airway nodules (papillomas) secondary to human papilloma virus (HPV) infection
Upper > lower airways
Invasive papillomatosis
Dissemination to lungs
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Benedict JJ et al: Recurrent respiratory papillomatosis: a 2020 perspective. Laryngoscope Investig Otolaryngol. 6(2):340-5, 2021
Lichtenberger JP 3rd et al: Primary lung tumors in children: radiologic-pathologic correlation from the radiologic pathology archives. Radiographics. 38(7):2151-72, 2018
Fortes HR et al: Recurrent respiratory papillomatosis: a state-of-the-art review. Respir Med. 126:116-21, 2017
Kalanjeri S et al: Diffuse tracheal papillomatosis. Am J Respir Crit Care Med. 195(1):134-5, 2017
Jhun BW et al: The clinical, radiological, and bronchoscopic findings and outcomes in patients with benign tracheobronchial tumors. Yonsei Med J. 55(1):84-91, 2014
Yu JP et al: Heterogeneous 18F-FDG uptake in recurrent respiratory papillomatosis. Clin Nucl Med. 38(5):387-9, 2013
Colt HG et al: Multimodality bronchoscopic imaging of recurrent respiratory papillomatosis. Laryngoscope. 120(3):468-72, 2010
Marchiori E et al: Tracheobronchial papillomatosis with diffuse cavitary lung lesions. Pediatr Radiol. 40(7):1301-2; author reply 1303, 2010
Prince JS et al: Nonneoplastic lesions of the tracheobronchial wall: radiologic findings with bronchoscopic correlation. Radiographics. 22 Spec No(S215-30, 2002
Guillou L et al: Squamous cell carcinoma of the lung in a nonsmoking, nonirradiated patient with juvenile laryngotracheal papillomatosis. Evidence of human papillomavirus-11 DNA in both carcinoma and papillomas. Am J Surg Pathol. 15(9):891-8, 1991
Kramer SS et al: Pulmonary manifestations of juvenile laryngotracheal papillomatosis. AJR Am J Roentgenol. 144(4):687-94, 1985
Godwin JD et al: Multiple, thin-walled cystic lesions of the lung. AJR Am J Roentgenol. 135(3):593-604, 1980
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
Recurrent respiratory papillomatosis (RRP)
Definitions
Airway nodules (papillomas) secondary to human papilloma virus (HPV) infection
Upper > lower airways
Invasive papillomatosis
Dissemination to lungs
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Benedict JJ et al: Recurrent respiratory papillomatosis: a 2020 perspective. Laryngoscope Investig Otolaryngol. 6(2):340-5, 2021
Lichtenberger JP 3rd et al: Primary lung tumors in children: radiologic-pathologic correlation from the radiologic pathology archives. Radiographics. 38(7):2151-72, 2018
Fortes HR et al: Recurrent respiratory papillomatosis: a state-of-the-art review. Respir Med. 126:116-21, 2017
Kalanjeri S et al: Diffuse tracheal papillomatosis. Am J Respir Crit Care Med. 195(1):134-5, 2017
Jhun BW et al: The clinical, radiological, and bronchoscopic findings and outcomes in patients with benign tracheobronchial tumors. Yonsei Med J. 55(1):84-91, 2014
Yu JP et al: Heterogeneous 18F-FDG uptake in recurrent respiratory papillomatosis. Clin Nucl Med. 38(5):387-9, 2013
Colt HG et al: Multimodality bronchoscopic imaging of recurrent respiratory papillomatosis. Laryngoscope. 120(3):468-72, 2010
Marchiori E et al: Tracheobronchial papillomatosis with diffuse cavitary lung lesions. Pediatr Radiol. 40(7):1301-2; author reply 1303, 2010
Prince JS et al: Nonneoplastic lesions of the tracheobronchial wall: radiologic findings with bronchoscopic correlation. Radiographics. 22 Spec No(S215-30, 2002
Guillou L et al: Squamous cell carcinoma of the lung in a nonsmoking, nonirradiated patient with juvenile laryngotracheal papillomatosis. Evidence of human papillomavirus-11 DNA in both carcinoma and papillomas. Am J Surg Pathol. 15(9):891-8, 1991
Kramer SS et al: Pulmonary manifestations of juvenile laryngotracheal papillomatosis. AJR Am J Roentgenol. 144(4):687-94, 1985
Godwin JD et al: Multiple, thin-walled cystic lesions of the lung. AJR Am J Roentgenol. 135(3):593-604, 1980
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