Transient Bone Marrow Edema and Regional Migratory Osteoporosis
Cheryl A. Petersilge, MD, MBA
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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Definitions
Transient bone marrow edema syndrome: Painful bone marrow edema centered around joints; of unknown etiology and self-limited
Transient regional osteoporosis (TRO): Likely subset of transient bone marrow edema syndrome that shows bone marrow edema and radiographic osteoporosis
Regional migratory osteoporosis: TRO that shows migratory pattern
Transient osteoporosis of hip (TOH): TRO, specifically of hip (most common location)
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
MR Findings
Bone Scan Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Joshi V et al: Painless transient bone marrow edema syndrome in a pediatric patient. Skeletal Radiol. 43(11):1615-9, 2014
Korompilias AV et al: Bone marrow edema syndrome. Skeletal Radiol. 38(5):425-36, 2009
Roemer FW et al: MRI-detected subchondral bone marrow signal alterations of the knee joint: terminology, imaging appearance, relevance and radiological differential diagnosis. Osteoarthritis Cartilage. 17(9):1115-31, 2009
Hofmann S: The painful bone marrow edema syndrome of the hip joint. Wien Klin Wochenschr. 117(4):111-20, 2005
Malizos KN et al: MR imaging findings in transient osteoporosis of the hip. Eur J Radiol. 50(3):238-44, 2004
Vande Berg BC et al: Idiopathic bone marrow edema lesions of the femoral head: predictive value of MR imaging findings. Radiology. 212(2):527-35, 1999
McCarthy EF: The pathology of transient regional osteoporosis. Iowa Orthop J. 18:35-42, 1998
Hayes CW et al: MR imaging of bone marrow edema pattern: transient osteoporosis, transient bone marrow edema syndrome, or osteonecrosis. Radiographics. 13(5):1001-11; discussion 1012, 1993
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Definitions
Transient bone marrow edema syndrome: Painful bone marrow edema centered around joints; of unknown etiology and self-limited
Transient regional osteoporosis (TRO): Likely subset of transient bone marrow edema syndrome that shows bone marrow edema and radiographic osteoporosis
Regional migratory osteoporosis: TRO that shows migratory pattern
Transient osteoporosis of hip (TOH): TRO, specifically of hip (most common location)
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
MR Findings
Bone Scan Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Joshi V et al: Painless transient bone marrow edema syndrome in a pediatric patient. Skeletal Radiol. 43(11):1615-9, 2014
Korompilias AV et al: Bone marrow edema syndrome. Skeletal Radiol. 38(5):425-36, 2009
Roemer FW et al: MRI-detected subchondral bone marrow signal alterations of the knee joint: terminology, imaging appearance, relevance and radiological differential diagnosis. Osteoarthritis Cartilage. 17(9):1115-31, 2009
Hofmann S: The painful bone marrow edema syndrome of the hip joint. Wien Klin Wochenschr. 117(4):111-20, 2005
Malizos KN et al: MR imaging findings in transient osteoporosis of the hip. Eur J Radiol. 50(3):238-44, 2004
Vande Berg BC et al: Idiopathic bone marrow edema lesions of the femoral head: predictive value of MR imaging findings. Radiology. 212(2):527-35, 1999
McCarthy EF: The pathology of transient regional osteoporosis. Iowa Orthop J. 18:35-42, 1998
Hayes CW et al: MR imaging of bone marrow edema pattern: transient osteoporosis, transient bone marrow edema syndrome, or osteonecrosis. Radiographics. 13(5):1001-11; discussion 1012, 1993
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