Makhoul IR et al: Neonatal transient renal failure with renal medullary hyperechogenicity: clinical and laboratory features. Pediatr Nephrol. 20(7):904-9, 2005
Ali US et al: Reversible renal medullary hyperechogenicity in neonatal hypernatremic dehydration. Pediatr Nephrol. 19(9):1050-2, 2004
Khoory BJ et al: Transient hyperechogenicity of the renal medullary pyramids: incidence in the healthy term newborn. Am J Perinatol. 16(9):463-8, 1999
Nakamura M et al: Hyperechoic renal papillae as a physiological finding in neonates. Clin Radiol. 54(4):233-6, 1999
Riebel TW et al: Transient renal medullary hyperechogenicity in ultrasound studies of neonates: is it a normal phenomenon and what are the causes? J Clin Ultrasound. 21(1):25-31, 1993
Hernanz-Schulman M: Hyperechoic renal medullary pyramids in infants and children. Radiology. 181(1):9-11, 1991
Shultz PK et al: Hyperechoic renal medullary pyramids in infants and children. Radiology. 181(1):163-7, 1991
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
Transient renal medullary hyperechogenicity
Descriptive term used in recent literature because etiology is unknown
Tamm-Horsfall proteinuria (THP)
Older term devised because of theory that THP precipitates in renal tubules → transient ↑ echogenicity
Theory has not been substantiated
Definitions
Temporary sonographic appearance of hyperechoic renal medullary pyramids in some normal neonates
Etiology is unclear (not linked to THP)
IMAGING
General Features
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Walawender L et al: Diagnosis and imaging of neonatal UTIs. Pediatr Neonatol. 61(2):195-200, 2020
Hemachandar R et al: Transient renal medullary hyperechogenicity in a term neonate. BMJ Case Rep. 2015, 2015
Maruyama H et al: Nephrocalcinosis and placental findings in neonatal bartter syndrome. AJP Rep. 3(1):21-4, 2013
Daneman A et al: Renal pyramids: focused sonography of normal and pathologic processes. Radiographics. 30(5):1287-307, 2010
Makhoul IR et al: Neonatal transient renal failure with renal medullary hyperechogenicity: clinical and laboratory features. Pediatr Nephrol. 20(7):904-9, 2005
Ali US et al: Reversible renal medullary hyperechogenicity in neonatal hypernatremic dehydration. Pediatr Nephrol. 19(9):1050-2, 2004
Khoory BJ et al: Transient hyperechogenicity of the renal medullary pyramids: incidence in the healthy term newborn. Am J Perinatol. 16(9):463-8, 1999
Nakamura M et al: Hyperechoic renal papillae as a physiological finding in neonates. Clin Radiol. 54(4):233-6, 1999
Riebel TW et al: Transient renal medullary hyperechogenicity in ultrasound studies of neonates: is it a normal phenomenon and what are the causes? J Clin Ultrasound. 21(1):25-31, 1993
Hernanz-Schulman M: Hyperechoic renal medullary pyramids in infants and children. Radiology. 181(1):9-11, 1991
Shultz PK et al: Hyperechoic renal medullary pyramids in infants and children. Radiology. 181(1):163-7, 1991
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