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KEY FACTS
Terminology
Imaging
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
- Transposition of great arteries (TGA)
- D-transposition
- Dextrotransposition
- Congenitally corrected TGA (cc-TGA)
- L-transposition
- Ventricular inversion
- Levotransposition
- Transposition of great arteries (TGA)
Definitions
- TGA: Ventriculoarterial (VA) discordance
- Aorta arises from right ventricle (RV)
- Pulmonary artery (PA) arises from left ventricle (LV)
- Further distinguished by presence/absence of ventricular septal defect (VSD)
- cc-TGA: Atrioventricular (AV) and VA discordance
- Right atrium → LV → PA
- Left atrium → RV → aorta
- TGA: Ventriculoarterial (VA) discordance
IMAGING
General Features
Echocardiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Hautala J et al: Perinatal and perioperative factors associated with mortality and an increased need for hospital care in infants with transposition of the great arteries: a nationwide 11-year population-based cohort. Acta Obstet Gynecol Scand. 99(12):1728-35, 2020
- Walter C et al: Comprehensive functional echocardiographic assessment of transposition of the great arteries: from fetus to newborn. Pediatr Cardiol. 41(4):687-94, 2020
- Kutty S et al: Contemporary management and outcomes in congenitally corrected transposition of the great arteries. Heart. 104(14):1148-55, 2018
- Tuo G et al: Prenatal echocardiographic assessment of foramen ovale appearance in fetuses with D-transposition of the great arteries and impact on neonatal outcome. Fetal Diagn Ther. 42(1):48-56, 2017
- Brandt JS et al: Utility of a single 3-vessel view in the evaluation of the ventricular outflow tracts. J Ultrasound Med. 34(8):1415-21, 2015
- Debost-Legrand A et al: Impact of prenatal diagnosis on the outcome of patients with a transposition of great arteries: a 24-year population-based study. Birth Defects Res A Clin Mol Teratol. 106(3):178-84, 2015
- Escobar-Diaz MC et al: Prenatal diagnosis of transposition of the great arteries over a 20-year period: improved but imperfect. Ultrasound Obstet Gynecol. 45(6):678-82, 2015
- Palatnik A et al: Is the "I-sign" in the 3-vessel and trachea view a valid tool for prenatal diagnosis of D-transposition of the great arteries? J Ultrasound Med. 34(7):1329-35, 2015
- Wolter A et al: Fetal cardiac axis in fetuses with conotruncal anomalies. Ultraschall Med. ePub, 2015
- Villafañe J et al: D-transposition of the great arteries: the current era of the arterial switch operation. J Am Coll Cardiol. 64(5):498-511, 2014
- Hörer J et al: Improvement in long-term survival after hospital discharge but not in freedom from reoperation after the change from atrial to arterial switch for transposition of the great arteries. J Thorac Cardiovasc Surg. 137(2):347-54, 2009
- Langley SM et al: Midterm results after restoration of the morphologically left ventricle to the systemic circulation in patients with congenitally corrected transposition of the great arteries. J Thorac Cardiovasc Surg. 125(6):1229-41, 2003
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
- Transposition of great arteries (TGA)
- D-transposition
- Dextrotransposition
- Congenitally corrected TGA (cc-TGA)
- L-transposition
- Ventricular inversion
- Levotransposition
- Transposition of great arteries (TGA)
Definitions
- TGA: Ventriculoarterial (VA) discordance
- Aorta arises from right ventricle (RV)
- Pulmonary artery (PA) arises from left ventricle (LV)
- Further distinguished by presence/absence of ventricular septal defect (VSD)
- cc-TGA: Atrioventricular (AV) and VA discordance
- Right atrium → LV → PA
- Left atrium → RV → aorta
- TGA: Ventriculoarterial (VA) discordance
IMAGING
General Features
Echocardiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Hautala J et al: Perinatal and perioperative factors associated with mortality and an increased need for hospital care in infants with transposition of the great arteries: a nationwide 11-year population-based cohort. Acta Obstet Gynecol Scand. 99(12):1728-35, 2020
- Walter C et al: Comprehensive functional echocardiographic assessment of transposition of the great arteries: from fetus to newborn. Pediatr Cardiol. 41(4):687-94, 2020
- Kutty S et al: Contemporary management and outcomes in congenitally corrected transposition of the great arteries. Heart. 104(14):1148-55, 2018
- Tuo G et al: Prenatal echocardiographic assessment of foramen ovale appearance in fetuses with D-transposition of the great arteries and impact on neonatal outcome. Fetal Diagn Ther. 42(1):48-56, 2017
- Brandt JS et al: Utility of a single 3-vessel view in the evaluation of the ventricular outflow tracts. J Ultrasound Med. 34(8):1415-21, 2015
- Debost-Legrand A et al: Impact of prenatal diagnosis on the outcome of patients with a transposition of great arteries: a 24-year population-based study. Birth Defects Res A Clin Mol Teratol. 106(3):178-84, 2015
- Escobar-Diaz MC et al: Prenatal diagnosis of transposition of the great arteries over a 20-year period: improved but imperfect. Ultrasound Obstet Gynecol. 45(6):678-82, 2015
- Palatnik A et al: Is the "I-sign" in the 3-vessel and trachea view a valid tool for prenatal diagnosis of D-transposition of the great arteries? J Ultrasound Med. 34(7):1329-35, 2015
- Wolter A et al: Fetal cardiac axis in fetuses with conotruncal anomalies. Ultraschall Med. ePub, 2015
- Villafañe J et al: D-transposition of the great arteries: the current era of the arterial switch operation. J Am Coll Cardiol. 64(5):498-511, 2014
- Hörer J et al: Improvement in long-term survival after hospital discharge but not in freedom from reoperation after the change from atrial to arterial switch for transposition of the great arteries. J Thorac Cardiovasc Surg. 137(2):347-54, 2009
- Langley SM et al: Midterm results after restoration of the morphologically left ventricle to the systemic circulation in patients with congenitally corrected transposition of the great arteries. J Thorac Cardiovasc Surg. 125(6):1229-41, 2003
