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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Idiopathic acute transverse myelitis (IATM)
Synonyms
Idiopathic transverse myelopathy
Definitions
Transverse myelitis (TM): Inflammatory disorder involving both halves of spinal cord, resulting in bilateral motor, sensory, & autonomic dysfunction
Pathogenetically heterogeneous inflammatory disorder of spinal cord
Must exclude other causes of spinal cord inflammation
IMAGING
General Features
CT Findings
MR Findings
Nonvascular Interventions
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Sorte DE et al: Longitudinally extensive myelopathy in children. Pediatr Radiol. 45(2):244-57; quiz 241-3, 2015
Landau YE et al: Pediatric neurologic complications associated with influenza A H1N1. Pediatr Neurol. 44(1):47-51, 2011
Scott TF et al: Evidence-based guideline: clinical evaluation and treatment of transverse myelitis: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology. 77(24):2128-34, 2011
Bigi S et al: Acute transverse myelitis in Lyme neuroborreliosis. Infection. 38(5):413-6, 2010
Agmon-Levin N et al: Transverse myelitis and vaccines: a multi-analysis. Lupus. 18(13):1198-204, 2009
Csábi G et al: Transverse myelitis as a rare, serious complication of Mycoplasma pneumoniae infection. Pediatr Neurol. 41(4):312-3, 2009
Kalra V et al: Childhood acute transverse myelitis: clinical profile, outcome, and association with antiganglioside antibodies. J Child Neurol. 24(4):466-71, 2009
Pandit L: Transverse myelitis spectrum disorders. Neurol India. 57(2):126-33, 2009
Lee JW et al: Diffusion tensor imaging in idiopathic acute transverse myelitis. AJR Am J Roentgenol. 191(2):W52-7, 2008
Andronikou S et al: MRI findings in acute idiopathic transverse myelopathy in children. Pediatr Radiol. 33(9):624-9, 2003
Kerr DA et al: Immunopathogenesis of acute transverse myelitis. Curr Opin Neurol. 15(3):339-47, 2002
Transverse Myelitis Consortium Working Group: proposed diagnostic criteria and nosology of acute transverse myelitis. Neurology. 59(4):499-505, 2002
Scotti G et al: Diagnosis and differential diagnosis of acute transverse myelopathy. The role of neuroradiological investigations and review of the literature. Neurol Sci. 22 Suppl 2:S69-73, 2001
Misra UK et al: Role of MRI in acute transverse myelitis. Neurol India. 47(4):253-4, 1999
Murthy JM et al: Acute transverse myelitis: MR characteristics. Neurol India. 47(4):290-3, 1999
Isoda H et al: MR imaging of acute transverse myelitis (myelopathy). Radiat Med. 16(3):179-86, 1998
Choi KH et al: Idiopathic transverse myelitis: MR characteristics. AJNR Am J Neuroradiol. 17(6):1151-60, 1996
Misra UK et al: A clinical, MRI and neurophysiological study of acute transverse myelitis. J Neurol Sci. 138(1-2):150-6, 1996
Campi A et al: Acute transverse myelopathy: spinal and cranial MR study with clinical follow-up. AJNR Am J Neuroradiol. 16(1):115-23, 1995
Jeffery DR et al: Transverse myelitis. Retrospective analysis of 33 cases, with differentiation of cases associated with multiple sclerosis and parainfectious events. Arch Neurol. 50(5):532-5, 1993
Dunne K et al: Acute transverse myelopathy in childhood. Dev Med Child Neurol. 28(2):198-204, 1986
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Idiopathic acute transverse myelitis (IATM)
Synonyms
Idiopathic transverse myelopathy
Definitions
Transverse myelitis (TM): Inflammatory disorder involving both halves of spinal cord, resulting in bilateral motor, sensory, & autonomic dysfunction
Pathogenetically heterogeneous inflammatory disorder of spinal cord
Must exclude other causes of spinal cord inflammation
IMAGING
General Features
CT Findings
MR Findings
Nonvascular Interventions
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Sorte DE et al: Longitudinally extensive myelopathy in children. Pediatr Radiol. 45(2):244-57; quiz 241-3, 2015
Landau YE et al: Pediatric neurologic complications associated with influenza A H1N1. Pediatr Neurol. 44(1):47-51, 2011
Scott TF et al: Evidence-based guideline: clinical evaluation and treatment of transverse myelitis: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology. 77(24):2128-34, 2011
Bigi S et al: Acute transverse myelitis in Lyme neuroborreliosis. Infection. 38(5):413-6, 2010
Agmon-Levin N et al: Transverse myelitis and vaccines: a multi-analysis. Lupus. 18(13):1198-204, 2009
Csábi G et al: Transverse myelitis as a rare, serious complication of Mycoplasma pneumoniae infection. Pediatr Neurol. 41(4):312-3, 2009
Kalra V et al: Childhood acute transverse myelitis: clinical profile, outcome, and association with antiganglioside antibodies. J Child Neurol. 24(4):466-71, 2009
Pandit L: Transverse myelitis spectrum disorders. Neurol India. 57(2):126-33, 2009
Lee JW et al: Diffusion tensor imaging in idiopathic acute transverse myelitis. AJR Am J Roentgenol. 191(2):W52-7, 2008
Andronikou S et al: MRI findings in acute idiopathic transverse myelopathy in children. Pediatr Radiol. 33(9):624-9, 2003
Kerr DA et al: Immunopathogenesis of acute transverse myelitis. Curr Opin Neurol. 15(3):339-47, 2002
Transverse Myelitis Consortium Working Group: proposed diagnostic criteria and nosology of acute transverse myelitis. Neurology. 59(4):499-505, 2002
Scotti G et al: Diagnosis and differential diagnosis of acute transverse myelopathy. The role of neuroradiological investigations and review of the literature. Neurol Sci. 22 Suppl 2:S69-73, 2001
Misra UK et al: Role of MRI in acute transverse myelitis. Neurol India. 47(4):253-4, 1999
Murthy JM et al: Acute transverse myelitis: MR characteristics. Neurol India. 47(4):290-3, 1999
Isoda H et al: MR imaging of acute transverse myelitis (myelopathy). Radiat Med. 16(3):179-86, 1998
Choi KH et al: Idiopathic transverse myelitis: MR characteristics. AJNR Am J Neuroradiol. 17(6):1151-60, 1996
Misra UK et al: A clinical, MRI and neurophysiological study of acute transverse myelitis. J Neurol Sci. 138(1-2):150-6, 1996
Campi A et al: Acute transverse myelopathy: spinal and cranial MR study with clinical follow-up. AJNR Am J Neuroradiol. 16(1):115-23, 1995
Jeffery DR et al: Transverse myelitis. Retrospective analysis of 33 cases, with differentiation of cases associated with multiple sclerosis and parainfectious events. Arch Neurol. 50(5):532-5, 1993
Dunne K et al: Acute transverse myelopathy in childhood. Dev Med Child Neurol. 28(2):198-204, 1986
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