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Tuberculosis
Lauren M. Ladd, MD; Cheryl A. Petersilge, MD, MBA
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KEY FACTS

  • Imaging

    • Clinical Issues

      TERMINOLOGY

      • Definitions

        • Cystic tuberculosis (TB): well-defined, intraosseous cystic lesions
        • Cold abscess: slowly developing abscesses, minimal surrounding inflammation, most common around spine
        • Phemister triad: findings seen in tuberculous arthritis
        • Pott disease: osteomyelitis of spine, tuberculous spondylitis
        • Pott puffy tumor: osteomyelitis of frontal bone with anterior cortex destruction, overlying soft tissue swelling

      IMAGING

      • General Features

        • Imaging Recommendations

          • Radiographic Findings

            • CT Findings

              • MR Findings

                • Nuclear Medicine Findings

                  • Image-Guided Biopsy

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Microscopic Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  Selected References

                                  1. Naselli N et al: MRI in differential diagnosis between tuberculous and pyogenic spondylodiscitis. Eur Spine J. ePub, 2021
                                  2. Kabiri EH et al: Tuberculous cold abscess of the chest wall: a clinical and surgical experience. Report of 16 cases(Case series). Ann Med Surg (Lond). 51:54-8, 2020
                                  3. Hogan JI et al: Mycobacterial musculoskeletal infections. Thorac Surg Clin. 29(1):85-94, 2019
                                  4. Hirji H et al: Paediatric acquired pathological vertebral collapse. Skeletal Radiol. 43(4):423-36, 2014
                                  5. Pattamapaspong N et al: Tuberculosis arthritis and tenosynovitis. Semin Musculoskelet Radiol. 15(5):459-69, 2011
                                  6. Shikhare SN et al: Tuberculous osteomyelitis and spondylodiscitis. Semin Musculoskelet Radiol. 15(5):446-58, 2011
                                  7. De Backer AI et al: Imaging features of extraaxial musculoskeletal tuberculosis. Indian J Radiol Imaging. 19(3):176-86, 2009
                                  8. Sanghvi DA et al: MRI features of tuberculosis of the knee. Skeletal Radiol. 38(3):267-73, 2009
                                  9. Burrill J et al: Tuberculosis: a radiologic review. Radiographics. 27(5):1255-73, 2007
                                  10. Teo HE et al: Skeletal tuberculosis in children. Pediatr Radiol. 34(11):853-60, 2004
                                  11. Andronikou S et al: "Spina ventosa"--tuberculous dactylitis. Arch Dis Child. 86(3):206, 2002
                                  12. Shanley DJ: Tuberculosis of the spine: imaging features. AJR Am J Roentgenol. 164(3):659-64, 1995
                                  Related Anatomy
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                                  Related Differential Diagnoses
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                                  References
                                  Tables

                                  Tables

                                  KEY FACTS

                                  • Imaging

                                    • Clinical Issues

                                      TERMINOLOGY

                                      • Definitions

                                        • Cystic tuberculosis (TB): well-defined, intraosseous cystic lesions
                                        • Cold abscess: slowly developing abscesses, minimal surrounding inflammation, most common around spine
                                        • Phemister triad: findings seen in tuberculous arthritis
                                        • Pott disease: osteomyelitis of spine, tuberculous spondylitis
                                        • Pott puffy tumor: osteomyelitis of frontal bone with anterior cortex destruction, overlying soft tissue swelling

                                      IMAGING

                                      • General Features

                                        • Imaging Recommendations

                                          • Radiographic Findings

                                            • CT Findings

                                              • MR Findings

                                                • Nuclear Medicine Findings

                                                  • Image-Guided Biopsy

                                                    DIFFERENTIAL DIAGNOSIS

                                                      PATHOLOGY

                                                      • General Features

                                                        • Microscopic Features

                                                          CLINICAL ISSUES

                                                          • Presentation

                                                            • Demographics

                                                              • Natural History & Prognosis

                                                                • Treatment

                                                                  Selected References

                                                                  1. Naselli N et al: MRI in differential diagnosis between tuberculous and pyogenic spondylodiscitis. Eur Spine J. ePub, 2021
                                                                  2. Kabiri EH et al: Tuberculous cold abscess of the chest wall: a clinical and surgical experience. Report of 16 cases(Case series). Ann Med Surg (Lond). 51:54-8, 2020
                                                                  3. Hogan JI et al: Mycobacterial musculoskeletal infections. Thorac Surg Clin. 29(1):85-94, 2019
                                                                  4. Hirji H et al: Paediatric acquired pathological vertebral collapse. Skeletal Radiol. 43(4):423-36, 2014
                                                                  5. Pattamapaspong N et al: Tuberculosis arthritis and tenosynovitis. Semin Musculoskelet Radiol. 15(5):459-69, 2011
                                                                  6. Shikhare SN et al: Tuberculous osteomyelitis and spondylodiscitis. Semin Musculoskelet Radiol. 15(5):446-58, 2011
                                                                  7. De Backer AI et al: Imaging features of extraaxial musculoskeletal tuberculosis. Indian J Radiol Imaging. 19(3):176-86, 2009
                                                                  8. Sanghvi DA et al: MRI features of tuberculosis of the knee. Skeletal Radiol. 38(3):267-73, 2009
                                                                  9. Burrill J et al: Tuberculosis: a radiologic review. Radiographics. 27(5):1255-73, 2007
                                                                  10. Teo HE et al: Skeletal tuberculosis in children. Pediatr Radiol. 34(11):853-60, 2004
                                                                  11. Andronikou S et al: "Spina ventosa"--tuberculous dactylitis. Arch Dis Child. 86(3):206, 2002
                                                                  12. Shanley DJ: Tuberculosis of the spine: imaging features. AJR Am J Roentgenol. 164(3):659-64, 1995