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Tumor Emboli
Carlos S. Restrepo, MD; Florian J. Fintelmann, MD, FRCPC
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Definitions

                • Embolic occlusion of pulmonary arteries by tumor cells
                  • Macroscopic fragments may occlude large caliber pulmonary arteries
                  • Microscopic tumor cell emboli may induce local coagulation and fibrocellular intimal proliferation: Pulmonary tumor thrombotic microangiopathy (PTTM)

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Angiographic Findings

                        • Nuclear Medicine Findings

                          • Imaging Recommendations

                            DIFFERENTIAL DIAGNOSIS

                              PATHOLOGY

                              • General Features

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Diagnosis

                                          • Treatment

                                            • Natural History & Prognosis

                                              DIAGNOSTIC CHECKLIST

                                              • Consider

                                                Selected References

                                                1. Franquet T et al: Uncommon thoracic manifestations from extrapulmonary tumors: computed tomography evaluation - Pictorial review. Respir Med. 168:105986, 2020
                                                2. Latchana N et al: Pulmonary tumor embolism secondary to soft tissue and bone sarcomas: a case report and literature review. World J Surg Oncol. 15(1):168, 2017
                                                3. Uruga H et al: Pulmonary tumor thrombotic microangiopathy: a clinical analysis of 30 autopsy cases. Intern Med. 52(12):1317-23, 2013
                                                4. Restrepo CS et al: Tumors of the pulmonary artery and veins. Semin Ultrasound CT MR. 33(6):580-90, 2012
                                                5. Sakuma M et al: Cancer and pulmonary embolism: thrombotic embolism, tumor embolism, and tumor invasion into a large vein. Circ J. 70(6):744-9, 2006
                                                6. Roberts KE et al: Pulmonary tumor embolism: a review of the literature. Am J Med. 115(3):228-32, 2003
                                                Related Anatomy
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                                                Related Differential Diagnoses
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                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Top Differential Diagnoses

                                                      • Pathology

                                                        • Clinical Issues

                                                          • Diagnostic Checklist

                                                            TERMINOLOGY

                                                            • Definitions

                                                              • Embolic occlusion of pulmonary arteries by tumor cells
                                                                • Macroscopic fragments may occlude large caliber pulmonary arteries
                                                                • Microscopic tumor cell emboli may induce local coagulation and fibrocellular intimal proliferation: Pulmonary tumor thrombotic microangiopathy (PTTM)

                                                            IMAGING

                                                            • General Features

                                                              • Radiographic Findings

                                                                • CT Findings

                                                                  • MR Findings

                                                                    • Angiographic Findings

                                                                      • Nuclear Medicine Findings

                                                                        • Imaging Recommendations

                                                                          DIFFERENTIAL DIAGNOSIS

                                                                            PATHOLOGY

                                                                            • General Features

                                                                              • Gross Pathologic & Surgical Features

                                                                                • Microscopic Features

                                                                                  CLINICAL ISSUES

                                                                                  • Presentation

                                                                                    • Demographics

                                                                                      • Diagnosis

                                                                                        • Treatment

                                                                                          • Natural History & Prognosis

                                                                                            DIAGNOSTIC CHECKLIST

                                                                                            • Consider

                                                                                              Selected References

                                                                                              1. Franquet T et al: Uncommon thoracic manifestations from extrapulmonary tumors: computed tomography evaluation - Pictorial review. Respir Med. 168:105986, 2020
                                                                                              2. Latchana N et al: Pulmonary tumor embolism secondary to soft tissue and bone sarcomas: a case report and literature review. World J Surg Oncol. 15(1):168, 2017
                                                                                              3. Uruga H et al: Pulmonary tumor thrombotic microangiopathy: a clinical analysis of 30 autopsy cases. Intern Med. 52(12):1317-23, 2013
                                                                                              4. Restrepo CS et al: Tumors of the pulmonary artery and veins. Semin Ultrasound CT MR. 33(6):580-90, 2012
                                                                                              5. Sakuma M et al: Cancer and pulmonary embolism: thrombotic embolism, tumor embolism, and tumor invasion into a large vein. Circ J. 70(6):744-9, 2006
                                                                                              6. Roberts KE et al: Pulmonary tumor embolism: a review of the literature. Am J Med. 115(3):228-32, 2003