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Undifferentiated Sarcoma
Michael P. Federle, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Synonyms

              • Undifferentiated embryonal sarcoma
              • Malignant mesenchymoma
            • Definitions

              • Primary malignant tumor of liver composed of primitive mesenchymal cells with partial, divergent differentiation

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      Selected References

                                      1. Ismail H et al: Treatment of undifferentiated embryonal sarcoma of the liver in children--single center experience. J Pediatr Surg. 48(11):2202-6, 2013
                                      2. Kalra N et al: Undifferentiated embryonal sarcoma of liver in an adult masquerading as complicated hydatid cyst. Ann Hepatol. 10(1):81-3, 2011
                                      3. Celikbilek M et al: Primary hepatic carcinosarcoma. Hepatobiliary Pancreat Dis Int. 10(1):101-3, 2011
                                      4. Gasljevic G et al: Undifferentiated (embryonal) liver sarcoma: synchronous and metachronous occurrence with neoplasms other than mesenchymal liver hamartoma. Ann Diagn Pathol. 15(4):250-6, 2011
                                      5. Oral A et al: A case of undifferentiated embryonic liver sarcoma mimicking cystic hydatid disease in an endemic region of the world. J Pediatr Surg. 46(11):e5-9, 2011
                                      6. Schoofs G et al: Hepatic rhabdomyosarcoma in an adult: a rare primary malignant liver tumor. Case report and literature review. Acta Gastroenterol Belg. 74(4):576-81, 2011
                                      7. Zacherl M et al: Surgery for liver metastases originating from sarcoma-case series. Langenbecks Arch Surg. 396(7):1083-91, 2011
                                      8. Goto H et al: Carcinosarcoma of the liver. Intern Med. 49(23):2577-82, 2010
                                      9. Massani M et al: Hepatic cystic lesion in adult: a challenging diagnosis of undifferentiated primary embryonal sarcoma. G Chir. 31(5):225-8, 2010
                                      10. Tsukada A et al: Embryonal sarcoma of the liver in an adult mimicking complicated hepatic cyst: MRI findings. J Magn Reson Imaging. 31(6):1477-80, 2010
                                      11. Upadhyaya M et al: Primary hepatic sarcomas in children--a single-center experience over 19 years. J Pediatr Surg. 45(11):2124-8, 2010
                                      12. Huang YJ et al: Education and imaging. Hepatobiliary and pancreatic: Huge hepatic carcinosarcoma. J Gastroenterol Hepatol. 24(5):929, 2009
                                      13. Kullar P et al: Primary hepatic embryonal sarcoma masquerading as metastatic ovarian cancer. World J Surg Oncol. 7:55, 2009
                                      14. Matthaei H et al: Long-term survival after surgery for primary hepatic sarcoma in adults. Arch Surg. 144(4):339-44; discussion 344, 2009
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Clinical Issues

                                              • Diagnostic Checklist

                                                TERMINOLOGY

                                                • Synonyms

                                                  • Undifferentiated embryonal sarcoma
                                                  • Malignant mesenchymoma
                                                • Definitions

                                                  • Primary malignant tumor of liver composed of primitive mesenchymal cells with partial, divergent differentiation

                                                IMAGING

                                                • General Features

                                                  • CT Findings

                                                    • MR Findings

                                                      • Ultrasonographic Findings

                                                        • Imaging Recommendations

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • Gross Pathologic & Surgical Features

                                                              • Microscopic Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Demographics

                                                                    • Natural History & Prognosis

                                                                      • Treatment

                                                                        DIAGNOSTIC CHECKLIST

                                                                        • Consider

                                                                          Selected References

                                                                          1. Ismail H et al: Treatment of undifferentiated embryonal sarcoma of the liver in children--single center experience. J Pediatr Surg. 48(11):2202-6, 2013
                                                                          2. Kalra N et al: Undifferentiated embryonal sarcoma of liver in an adult masquerading as complicated hydatid cyst. Ann Hepatol. 10(1):81-3, 2011
                                                                          3. Celikbilek M et al: Primary hepatic carcinosarcoma. Hepatobiliary Pancreat Dis Int. 10(1):101-3, 2011
                                                                          4. Gasljevic G et al: Undifferentiated (embryonal) liver sarcoma: synchronous and metachronous occurrence with neoplasms other than mesenchymal liver hamartoma. Ann Diagn Pathol. 15(4):250-6, 2011
                                                                          5. Oral A et al: A case of undifferentiated embryonic liver sarcoma mimicking cystic hydatid disease in an endemic region of the world. J Pediatr Surg. 46(11):e5-9, 2011
                                                                          6. Schoofs G et al: Hepatic rhabdomyosarcoma in an adult: a rare primary malignant liver tumor. Case report and literature review. Acta Gastroenterol Belg. 74(4):576-81, 2011
                                                                          7. Zacherl M et al: Surgery for liver metastases originating from sarcoma-case series. Langenbecks Arch Surg. 396(7):1083-91, 2011
                                                                          8. Goto H et al: Carcinosarcoma of the liver. Intern Med. 49(23):2577-82, 2010
                                                                          9. Massani M et al: Hepatic cystic lesion in adult: a challenging diagnosis of undifferentiated primary embryonal sarcoma. G Chir. 31(5):225-8, 2010
                                                                          10. Tsukada A et al: Embryonal sarcoma of the liver in an adult mimicking complicated hepatic cyst: MRI findings. J Magn Reson Imaging. 31(6):1477-80, 2010
                                                                          11. Upadhyaya M et al: Primary hepatic sarcomas in children--a single-center experience over 19 years. J Pediatr Surg. 45(11):2124-8, 2010
                                                                          12. Huang YJ et al: Education and imaging. Hepatobiliary and pancreatic: Huge hepatic carcinosarcoma. J Gastroenterol Hepatol. 24(5):929, 2009
                                                                          13. Kullar P et al: Primary hepatic embryonal sarcoma masquerading as metastatic ovarian cancer. World J Surg Oncol. 7:55, 2009
                                                                          14. Matthaei H et al: Long-term survival after surgery for primary hepatic sarcoma in adults. Arch Surg. 144(4):339-44; discussion 344, 2009