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Unresectable Lung Cancer
Terrance Healey, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Non-small cell lung cancer (NSCLC)
              • Small cell lung cancer (SCLC)
            • Definitions

              • Lung cancer for which surgery does not provide survival benefit: Clinical stages IIIB and IV

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • Nuclear Medicine Findings

                    • MR Findings

                      • Ultrasonographic Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Reporting Tips

                                            Selected References

                                            1. Betancourt-Cuellar SL et al: Pitfalls and limitations in non-small cell lung cancer staging. Semin Roentgenol. 50(3):175-82, 2015
                                            2. Murgu SD: Diagnosing and staging lung cancer involving the mediastinum. Chest. 147(5):1401-12, 2015
                                            3. Ohno Y et al: Three-way Comparison of Whole-Body MR, Coregistered Whole-Body FDG PET/MR, and Integrated Whole-Body FDG PET/CT Imaging: TNM and Stage Assessment Capability for Non-Small Cell Lung Cancer Patients. Radiology. 140936, 2015
                                            4. Ohri N et al: Pretreatment FDG-PET Metrics in Stage III Non-Small Cell Lung Cancer: ACRIN 6668/RTOG 0235. J Natl Cancer Inst. 107(4), 2015
                                            5. Reungwetwattana T et al: Chemotherapy for non-small-cell lung carcinoma: from a blanket approach to individual therapy. Semin Respir Crit Care Med. 32(1):78-93, 2011
                                            6. Kligerman S et al: A radiologic review of the new TNM classification for lung cancer. AJR Am J Roentgenol. 2010 Mar;194(3):562-73. Review. Erratum in: AJR Am J Roentgenol. 194(5):1404, 2010
                                            7. Paesmans M et al: Primary tumor standardized uptake value measured on fluorodeoxyglucose positron emission tomography is of prognostic value for survival in non-small cell lung cancer: update of a systematic review and meta-analysis by the European Lung Cancer Working Party for the International Association for the Study of Lung Cancer Staging Project. J Thorac Oncol. 5(5):612-9, 2010
                                            8. UyBico SJ et al: Lung cancer staging essentials: the new TNM staging system and potential imaging pitfalls. Radiographics. 30(5):1163-81, 2010
                                            9. Detterbeck FC et al: The new lung cancer staging system. Chest. 136(1):260-71, 2009
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Non-small cell lung cancer (NSCLC)
                                                        • Small cell lung cancer (SCLC)
                                                      • Definitions

                                                        • Lung cancer for which surgery does not provide survival benefit: Clinical stages IIIB and IV

                                                      IMAGING

                                                      • General Features

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            • Nuclear Medicine Findings

                                                              • MR Findings

                                                                • Ultrasonographic Findings

                                                                  • Imaging Recommendations

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Staging, Grading, & Classification

                                                                          • Microscopic Features

                                                                            CLINICAL ISSUES

                                                                            • Presentation

                                                                              • Demographics

                                                                                • Natural History & Prognosis

                                                                                  • Treatment

                                                                                    DIAGNOSTIC CHECKLIST

                                                                                    • Reporting Tips

                                                                                      Selected References

                                                                                      1. Betancourt-Cuellar SL et al: Pitfalls and limitations in non-small cell lung cancer staging. Semin Roentgenol. 50(3):175-82, 2015
                                                                                      2. Murgu SD: Diagnosing and staging lung cancer involving the mediastinum. Chest. 147(5):1401-12, 2015
                                                                                      3. Ohno Y et al: Three-way Comparison of Whole-Body MR, Coregistered Whole-Body FDG PET/MR, and Integrated Whole-Body FDG PET/CT Imaging: TNM and Stage Assessment Capability for Non-Small Cell Lung Cancer Patients. Radiology. 140936, 2015
                                                                                      4. Ohri N et al: Pretreatment FDG-PET Metrics in Stage III Non-Small Cell Lung Cancer: ACRIN 6668/RTOG 0235. J Natl Cancer Inst. 107(4), 2015
                                                                                      5. Reungwetwattana T et al: Chemotherapy for non-small-cell lung carcinoma: from a blanket approach to individual therapy. Semin Respir Crit Care Med. 32(1):78-93, 2011
                                                                                      6. Kligerman S et al: A radiologic review of the new TNM classification for lung cancer. AJR Am J Roentgenol. 2010 Mar;194(3):562-73. Review. Erratum in: AJR Am J Roentgenol. 194(5):1404, 2010
                                                                                      7. Paesmans M et al: Primary tumor standardized uptake value measured on fluorodeoxyglucose positron emission tomography is of prognostic value for survival in non-small cell lung cancer: update of a systematic review and meta-analysis by the European Lung Cancer Working Party for the International Association for the Study of Lung Cancer Staging Project. J Thorac Oncol. 5(5):612-9, 2010
                                                                                      8. UyBico SJ et al: Lung cancer staging essentials: the new TNM staging system and potential imaging pitfalls. Radiographics. 30(5):1163-81, 2010
                                                                                      9. Detterbeck FC et al: The new lung cancer staging system. Chest. 136(1):260-71, 2009