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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Definitions
- Interstitial ectopic pregnancy (EP): Preferred term for pregnancy occurring in interstitial (intramural) portion of fallopian tube
- Synonym: Intramural ectopic pregnancy
- Cornual EP: Often used interchangeably with interstitial ectopic; more appropriately applied to pregnancy in the cornua of an abnormal uterus (horn of uni- or bicornuate uterus or lateral half of septate uterus)
- Angular pregnancy: Pregnancy implanted at lateral angle of uterine cavity by ostium, medial to interstitial tube
- Uterine scar EP: Implantation of pregnancy at the site of previous uterine surgery, e.g., myomectomy or cesarean section (C-section)
- Synonyms: Scar EP, C-section scar EP
- Cervical EP: Gestational sac (GS) implanted in the wall of the cervix below the level of the internal cervical os
- Ovarian EP: Intraovarian implantation of a GS
- Abdominal EP: Implantation in the peritoneal cavity
- Primary: Direct peritoneal implantation; secondary: Re-implantation of ruptured extrauterine pregnancy in peritoneal cavity (more common than primary form)
- Heterotopic pregnancy: Concurrent intrauterine and ectopic pregnancies
- Interstitial ectopic pregnancy (EP): Preferred term for pregnancy occurring in interstitial (intramural) portion of fallopian tube
IMAGING
General Features
Ultrasonographic Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Ghaneie A et al: Unusual Ectopic Pregnancies: Sonographic Findings and Implications for Management. J Ultrasound Med. 34(6):951-962, 2015
- Tanaka Y et al: Three-dimensional sonography in the differential diagnosis of interstitial, angular, and intrauterine pregnancies in a septate uterus. J Ultrasound Med. 33(11):2031-5, 2014
- Poon LC et al: How feasible is expectant management of interstitial ectopic pregnancy? Ultrasound Obstet Gynecol. Epub ahead of print, 2013
- Surbone A et al: Interstitial pregnancies' diagnosis and management: an eleven cases series. Swiss Med Wkly. 143:w13736, 2013
- Wu R et al: Magnetic resonance imaging as an adjunct to ultrasound in evaluating cesarean scar ectopic pregnancy. J Clin Imaging Sci. 3:16, 2013
- Parker RA 3rd et al: MR imaging findings of ectopic pregnancy: a pictorial review. Radiographics. 32(5):1445-60; discussion 1460-2, 2012
- Verma U et al: Conservative management of nontubal ectopic pregnancies. Fertil Steril. 96(6):1391-1395, 2011
- Moawad NS et al: Current diagnosis and treatment of interstitial pregnancy. Am J Obstet Gynecol. 202(1):15-29, 2010
- Chetty M et al: Treating non-tubal ectopic pregnancy. Best Pract Res Clin Obstet Gynaecol. 23(4):529-38, 2009
- Mavrelos D et al: Ultrasound diagnosis of ectopic pregnancy in the non-communicating horn of a unicornuate uterus (cornual pregnancy). Ultrasound Obstet Gynecol. 30(5):765-70, 2007
- Oliver R et al: Management of extra-tubal and rare ectopic pregnancies: case series and review of current literature. Arch Gynecol Obstet. 276(2):125-31, 2007
- Chan LY et al: Pitfalls in diagnosis of interstitial pregnancy. Acta Obstet Gynecol Scand. 82(9):867-70, 2003
- Izquierdo LA et al: Three-dimensional transvaginal sonography of interstitial pregnancy. J Clin Ultrasound. 31(9):484-7, 2003
- Bouyer J et al: Sites of ectopic pregnancy: a 10 year population-based study of 1800 cases. Hum Reprod. 17(12):3224-30, 2002
- Ackerman TE et al: Interstitial line: sonographic finding in interstitial (cornual) ectopic pregnancy. Radiology. 189(1):83-7, 1993
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Definitions
- Interstitial ectopic pregnancy (EP): Preferred term for pregnancy occurring in interstitial (intramural) portion of fallopian tube
- Synonym: Intramural ectopic pregnancy
- Cornual EP: Often used interchangeably with interstitial ectopic; more appropriately applied to pregnancy in the cornua of an abnormal uterus (horn of uni- or bicornuate uterus or lateral half of septate uterus)
- Angular pregnancy: Pregnancy implanted at lateral angle of uterine cavity by ostium, medial to interstitial tube
- Uterine scar EP: Implantation of pregnancy at the site of previous uterine surgery, e.g., myomectomy or cesarean section (C-section)
- Synonyms: Scar EP, C-section scar EP
- Cervical EP: Gestational sac (GS) implanted in the wall of the cervix below the level of the internal cervical os
- Ovarian EP: Intraovarian implantation of a GS
- Abdominal EP: Implantation in the peritoneal cavity
- Primary: Direct peritoneal implantation; secondary: Re-implantation of ruptured extrauterine pregnancy in peritoneal cavity (more common than primary form)
- Heterotopic pregnancy: Concurrent intrauterine and ectopic pregnancies
- Interstitial ectopic pregnancy (EP): Preferred term for pregnancy occurring in interstitial (intramural) portion of fallopian tube
IMAGING
General Features
Ultrasonographic Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Ghaneie A et al: Unusual Ectopic Pregnancies: Sonographic Findings and Implications for Management. J Ultrasound Med. 34(6):951-962, 2015
- Tanaka Y et al: Three-dimensional sonography in the differential diagnosis of interstitial, angular, and intrauterine pregnancies in a septate uterus. J Ultrasound Med. 33(11):2031-5, 2014
- Poon LC et al: How feasible is expectant management of interstitial ectopic pregnancy? Ultrasound Obstet Gynecol. Epub ahead of print, 2013
- Surbone A et al: Interstitial pregnancies' diagnosis and management: an eleven cases series. Swiss Med Wkly. 143:w13736, 2013
- Wu R et al: Magnetic resonance imaging as an adjunct to ultrasound in evaluating cesarean scar ectopic pregnancy. J Clin Imaging Sci. 3:16, 2013
- Parker RA 3rd et al: MR imaging findings of ectopic pregnancy: a pictorial review. Radiographics. 32(5):1445-60; discussion 1460-2, 2012
- Verma U et al: Conservative management of nontubal ectopic pregnancies. Fertil Steril. 96(6):1391-1395, 2011
- Moawad NS et al: Current diagnosis and treatment of interstitial pregnancy. Am J Obstet Gynecol. 202(1):15-29, 2010
- Chetty M et al: Treating non-tubal ectopic pregnancy. Best Pract Res Clin Obstet Gynaecol. 23(4):529-38, 2009
- Mavrelos D et al: Ultrasound diagnosis of ectopic pregnancy in the non-communicating horn of a unicornuate uterus (cornual pregnancy). Ultrasound Obstet Gynecol. 30(5):765-70, 2007
- Oliver R et al: Management of extra-tubal and rare ectopic pregnancies: case series and review of current literature. Arch Gynecol Obstet. 276(2):125-31, 2007
- Chan LY et al: Pitfalls in diagnosis of interstitial pregnancy. Acta Obstet Gynecol Scand. 82(9):867-70, 2003
- Izquierdo LA et al: Three-dimensional transvaginal sonography of interstitial pregnancy. J Clin Ultrasound. 31(9):484-7, 2003
- Bouyer J et al: Sites of ectopic pregnancy: a 10 year population-based study of 1800 cases. Hum Reprod. 17(12):3224-30, 2002
- Ackerman TE et al: Interstitial line: sonographic finding in interstitial (cornual) ectopic pregnancy. Radiology. 189(1):83-7, 1993
