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Upper Tract Urothelial Carcinoma
Hammed Ninalowo, MD; Jade Wong-You-Cheong, MBChB, MRCP, FRCR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Upper tract urothelial carcinoma (UTUC)
              • Synonyms

                • Upper tract transitional cell carcinoma (TCC)
              • Definitions

                • Malignant tumor of transitional epithelium extending from calyces to ureteral orifices

              IMAGING

              • General Features

                • Ultrasonographic Findings

                  • Pyelography

                    • CT Findings

                      • MR Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    • Urine Cytology

                                      CLINICAL ISSUES

                                      • Presentation

                                        • Demographics

                                          • Natural History & Prognosis

                                            • Treatment

                                              DIAGNOSTIC CHECKLIST

                                              • Consider

                                                • Image Interpretation Pearls

                                                  Selected References

                                                  1. Gayer G et al: The renal sinus--transitional cell carcinoma and its mimickers on computed tomography. Semin Ultrasound CT MR. 35(3):308-19, 2014
                                                  2. RouprĂȘt M et al: European guidelines on upper tract urothelial carcinomas: 2013 update. Eur Urol. 63(6):1059-71, 2013
                                                  3. Xue LY et al: Evaluation of renal urothelial carcinoma by contrast-enhanced ultrasonography. Eur J Radiol. 82(4):e151-7, 2013
                                                  4. Lee EK et al: Imaging of urothelial cancers: what the urologist needs to know. AJR Am J Roentgenol. 196(6):1249-54, 2011
                                                  5. Vikram R et al: Imaging and staging of transitional cell carcinoma: part 2, upper urinary tract. AJR Am J Roentgenol. 192(6):1488-93, 2009
                                                  6. Park S et al: The impact of tumor location on prognosis of transitional cell carcinoma of the upper urinary tract. J Urol. 171(2 Pt 1):621-5, 2004
                                                  Related Anatomy
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                                                  Related Differential Diagnoses
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                                                  References
                                                  Tables

                                                  Tables

                                                  KEY FACTS

                                                  • Terminology

                                                    • Imaging

                                                      • Top Differential Diagnoses

                                                        • Pathology

                                                          • Clinical Issues

                                                            • Diagnostic Checklist

                                                              TERMINOLOGY

                                                              • Abbreviations

                                                                • Upper tract urothelial carcinoma (UTUC)
                                                              • Synonyms

                                                                • Upper tract transitional cell carcinoma (TCC)
                                                              • Definitions

                                                                • Malignant tumor of transitional epithelium extending from calyces to ureteral orifices

                                                              IMAGING

                                                              • General Features

                                                                • Ultrasonographic Findings

                                                                  • Pyelography

                                                                    • CT Findings

                                                                      • MR Findings

                                                                        • Imaging Recommendations

                                                                          DIFFERENTIAL DIAGNOSIS

                                                                            PATHOLOGY

                                                                            • General Features

                                                                              • Staging, Grading, & Classification

                                                                                • Gross Pathologic & Surgical Features

                                                                                  • Microscopic Features

                                                                                    • Urine Cytology

                                                                                      CLINICAL ISSUES

                                                                                      • Presentation

                                                                                        • Demographics

                                                                                          • Natural History & Prognosis

                                                                                            • Treatment

                                                                                              DIAGNOSTIC CHECKLIST

                                                                                              • Consider

                                                                                                • Image Interpretation Pearls

                                                                                                  Selected References

                                                                                                  1. Gayer G et al: The renal sinus--transitional cell carcinoma and its mimickers on computed tomography. Semin Ultrasound CT MR. 35(3):308-19, 2014
                                                                                                  2. RouprĂȘt M et al: European guidelines on upper tract urothelial carcinomas: 2013 update. Eur Urol. 63(6):1059-71, 2013
                                                                                                  3. Xue LY et al: Evaluation of renal urothelial carcinoma by contrast-enhanced ultrasonography. Eur J Radiol. 82(4):e151-7, 2013
                                                                                                  4. Lee EK et al: Imaging of urothelial cancers: what the urologist needs to know. AJR Am J Roentgenol. 196(6):1249-54, 2011
                                                                                                  5. Vikram R et al: Imaging and staging of transitional cell carcinoma: part 2, upper urinary tract. AJR Am J Roentgenol. 192(6):1488-93, 2009
                                                                                                  6. Park S et al: The impact of tumor location on prognosis of transitional cell carcinoma of the upper urinary tract. J Urol. 171(2 Pt 1):621-5, 2004