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Ureteropelvic Junction Obstruction
Emily Edwards, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Ureteropelvic junction (UPJ) obstruction
            • Synonyms

              • Congenital hydronephrosis
            • Definitions

              • Upper urinary tract obstruction at junction of extrarenal pelvis and ureter

            IMAGING

            • General Features

              • Ultrasonographic Findings

                • Imaging Recommendations

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Staging, Grading, & Classification

                        • Gross Pathologic & Surgical Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Image Interpretation Pearls

                                    Selected References

                                    1. Passoni NM et al: Managing ureteropelvic junction obstruction in the young infant. Front Pediatr. 8:242, 2020
                                    2. Babu R et al: Pathological changes in ureterovesical and ureteropelvic junction obstruction explained by fetal ureter histology. J Pediatr Urol. 15(3):240.e1-7, 2019
                                    3. Arena S et al: A long-term follow-up in conservative management of unilateral ureteropelvic junction obstruction with poor drainage and good renal function. Eur J Pediatr. 177(12):1761-65, 2018
                                    4. Jiang D et al: Functional and morphological outcomes of pyeloplasty at different ages in prenatally diagnosed Society of Fetal Urology grades 3-4 ureteropelvic junction obstruction: Is it safe to wait? Urology. 101:45-49, 2017
                                    5. Weitz M et al: Primary non-surgical management of unilateral ureteropelvic junction obstruction in children: a systematic review. Pediatr Nephrol. 32(12):2203-13, 2017
                                    6. Mudrik-Zohar H et al: Prenatal sonographic predictors of postnatal pyeloplasty in fetuses with isolated hydronephrosis. Prenat Diagn. 35(2):142-7, 2015
                                    7. Rianthavorn P et al: Diagnostic accuracy of neonatal kidney ultrasound in children having antenatal hydronephrosis without ureter and bladder abnormalities. World J Urol. 33(10): 1645-50, 2015
                                    8. Kumar M et al: Fetal renal anomaly: factors that predict survival. J Pediatr Urol. 10(6):1001-7, 2014
                                    9. Nguyen HT et al: Multidisciplinary consensus on the classification of prenatal and postnatal urinary tract dilation (UTD classification system). J Pediatr Urol. 10(6):982-98, 2014
                                    10. Ross SS et al: Observation of infants with SFU grades 3-4 hydronephrosis: worsening drainage with serial diuresis renography indicates surgical intervention and helps prevent loss of renal function. J Pediatr Urol. 7(3):266-71, 2011
                                    11. Yang Y et al: Long-term follow-up and management of prenatally detected, isolated hydronephrosis. J Pediatr Surg. 45(8):1701-6, 2010
                                    12. Thomas DF: Prenatally diagnosed urinary tract abnormalities: long-term outcome. Semin Fetal Neonatal Med. 13(3):189-95, 2008
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Clinical Issues

                                            • Diagnostic Checklist

                                              TERMINOLOGY

                                              • Abbreviations

                                                • Ureteropelvic junction (UPJ) obstruction
                                              • Synonyms

                                                • Congenital hydronephrosis
                                              • Definitions

                                                • Upper urinary tract obstruction at junction of extrarenal pelvis and ureter

                                              IMAGING

                                              • General Features

                                                • Ultrasonographic Findings

                                                  • Imaging Recommendations

                                                    DIFFERENTIAL DIAGNOSIS

                                                      PATHOLOGY

                                                      • General Features

                                                        • Staging, Grading, & Classification

                                                          • Gross Pathologic & Surgical Features

                                                            CLINICAL ISSUES

                                                            • Presentation

                                                              • Demographics

                                                                • Natural History & Prognosis

                                                                  • Treatment

                                                                    DIAGNOSTIC CHECKLIST

                                                                    • Image Interpretation Pearls

                                                                      Selected References

                                                                      1. Passoni NM et al: Managing ureteropelvic junction obstruction in the young infant. Front Pediatr. 8:242, 2020
                                                                      2. Babu R et al: Pathological changes in ureterovesical and ureteropelvic junction obstruction explained by fetal ureter histology. J Pediatr Urol. 15(3):240.e1-7, 2019
                                                                      3. Arena S et al: A long-term follow-up in conservative management of unilateral ureteropelvic junction obstruction with poor drainage and good renal function. Eur J Pediatr. 177(12):1761-65, 2018
                                                                      4. Jiang D et al: Functional and morphological outcomes of pyeloplasty at different ages in prenatally diagnosed Society of Fetal Urology grades 3-4 ureteropelvic junction obstruction: Is it safe to wait? Urology. 101:45-49, 2017
                                                                      5. Weitz M et al: Primary non-surgical management of unilateral ureteropelvic junction obstruction in children: a systematic review. Pediatr Nephrol. 32(12):2203-13, 2017
                                                                      6. Mudrik-Zohar H et al: Prenatal sonographic predictors of postnatal pyeloplasty in fetuses with isolated hydronephrosis. Prenat Diagn. 35(2):142-7, 2015
                                                                      7. Rianthavorn P et al: Diagnostic accuracy of neonatal kidney ultrasound in children having antenatal hydronephrosis without ureter and bladder abnormalities. World J Urol. 33(10): 1645-50, 2015
                                                                      8. Kumar M et al: Fetal renal anomaly: factors that predict survival. J Pediatr Urol. 10(6):1001-7, 2014
                                                                      9. Nguyen HT et al: Multidisciplinary consensus on the classification of prenatal and postnatal urinary tract dilation (UTD classification system). J Pediatr Urol. 10(6):982-98, 2014
                                                                      10. Ross SS et al: Observation of infants with SFU grades 3-4 hydronephrosis: worsening drainage with serial diuresis renography indicates surgical intervention and helps prevent loss of renal function. J Pediatr Urol. 7(3):266-71, 2011
                                                                      11. Yang Y et al: Long-term follow-up and management of prenatally detected, isolated hydronephrosis. J Pediatr Surg. 45(8):1701-6, 2010
                                                                      12. Thomas DF: Prenatally diagnosed urinary tract abnormalities: long-term outcome. Semin Fetal Neonatal Med. 13(3):189-95, 2008