Bookmarks
KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Definitions
- Müllerian adenosarcoma
- Subtype of mixed epithelial-mesenchymal tumors, possibly spectrum with adenosarcoma as intermediate malignant potential
- Adenofibroma: Benign epithelial and mesenchymal components
- Adenosarcoma: Benign epithelial and malignant mesenchymal components
- Carcinosarcoma: Malignant epithelial and mesenchymal components
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Lugo Santiago N et al: Management and survival of patients with mullerian adenosarcoma of the cervix without sarcomatous overgrowth desiring fertility preservation, a case report and review of the literature. Gynecol Oncol Rep. 32:100525, 2020
- Huang YT et al: Current status of magnetic resonance imaging in patients with malignant uterine neoplasms: a review. Korean J Radiol. 20(1):18-33, 2019
- Kudela E et al: Mullerian adenosarcomas of the uterine cervix with sarcomatous overgrowth. Curr Probl Cancer. 43(4):371-6, 2019
- Parra-Herran C et al: Uterine mesenchymal tumors: update on classification, staging, and molecular features. Surg Pathol Clin. 12(2):363-96, 2019
- Vilches Jimenez JC et al: Diagnostic challenges: low-grade adenosarcoma on deep endometriosis. BMC Womens Health. 19(1):124, 2019
- Yuan Z et al: Uterine adenosarcoma: a retrospective 12-year single-center study. Front Oncol. 9:237, 2019
- Nathenson MJ et al: Prognostic factors for uterine adenosarcoma: a review. Expert Rev Anticancer Ther. 18(11):1093-100, 2018
- Nathenson MJ et al: The importance of lymphovascular invasion in uterine adenosarcomas: analysis of clinical, prognostic, and treatment outcomes. Int J Gynecol Cancer. 28(7):1297-310, 2018
- Ulrich UA et al: Uterine adenosarcoma. Oncol Res Treat. 41(11):693-6, 2018
- Nathenson MJ et al: Uterine Adenosarcoma: a review. Curr Oncol Rep. 18(11):68, 2016
- Pinto A et al: Uterine adenosarcoma. Arch Pathol Lab Med. 140(3):286-90, 2016
- Seagle BL et al: Survival of women with mullerian adenosarcoma: a National Cancer Data Base study. Gynecol Oncol. 143(3):636-41, 2016
- Chin PS et al: Diagnosis and management of müllerian adenosarcoma of the uterine cervix. Int J Gynaecol Obstet. 121(3):229-32, 2013
- Hirschowitz L et al: Intravascular adenomyomatosis: expanding the morphologic spectrum of intravascular leiomyomatosis. Am J Surg Pathol. 37(9):1395-400, 2013
- Lee TY et al: Synchronous occurrence of primary malignant mixed müllerian tumor in ovary and uterus. Obstet Gynecol Sci. 56(4):269-72, 2013
- Novetsky AP et al: Management of sarcomas of the uterus. Curr Opin Oncol. 25(5):546-52, 2013
- Sutton G: Uterine sarcomas 2013. Gynecol Oncol. 130(1):3-5, 2013
- Tanner EJ et al: Management of uterine adenosarcomas with and without sarcomatous overgrowth. Gynecol Oncol. 129(1):140-4, 2013
- Tirumani SH et al: Current concepts in the imaging of uterine sarcoma. Abdom Imaging. 38(2):397-411, 2013
- Yu J et al: [Clinicopathologic characteristics of müllerian adenosarcoma of uterus:a comparative analysis of 7 cases before and after surgery.] Zhonghua Bing Li Xue Za Zhi. 42(8):547-8, 2013
- Akhavan A et al: Uterine adenosarcoma in a patient with history of breast cancer and long-term tamoxifen consumption. BMJ Case Rep. 2012, 2012
- Tropé CG et al: Diagnosis and treatment of sarcoma of the uterus. A review. Acta Oncol. 51(6):694-705, 2012
- Sameshima N et al: So-called 'adenosarcoma' of the kidney a novel adult renal tumor with a cystic appearance. Pathol Int. 61(5):313-8, 2011
- Yoshizako T et al: MR imaging of uterine adenosarcoma: case report and literature review. Magn Reson Med Sci. 10(4):251-4, 2011
- Takeuchi M et al: Adenosarcoma of the uterus: magnetic resonance imaging characteristics. Clin Imaging. 33(3):244-7, 2009
- Soh E et al: Magnetic resonance imaging findings of tamoxifen-associated uterine müllerian adenosarcoma: a case report. Acta Radiol. 49(7):848-51, 2008
- Tjalma WA et al: Mullerian adenosarcoma of the uterus associated with long-term oral contraceptive use. Eur J Obstet Gynecol Reprod Biol. 119(2):253-4, 2005
- Crade M et al: Pedicle sign and diagnosis of endometrial adenosarcoma. J Ultrasound Med. 23(9):1217-9, 2004
- Lee EJ et al: Polypoid adenomyomas: sonohysterographic and color Doppler findings with histopathologic correlation. J Ultrasound Med. 23(11):1421-9; quiz 1431, 2004
- Tinar S et al: Adenosarcoma of the uterus: a case report. MedGenMed. 6(1):51, 2004
- Chourmouzi D et al: Sonography and MRI of tamoxifen-associated mullerian adenosarcoma of the uterus. AJR Am J Roentgenol. 181(6):1673-5, 2003
- Rha SE et al: CT and MRI of uterine sarcomas and their mimickers. AJR Am J Roentgenol. 181(5):1369-74, 2003
- Hann LE et al: Sonohysterography for evaluation of the endometrium in women treated with tamoxifen. AJR Am J Roentgenol. 177(2):337-42, 2001
- Krivak TC et al: Uterine adenosarcoma with sarcomatous overgrowth versus uterine carcinosarcoma: comparison of treatment and survival. Gynecol Oncol. 83(1):89-94, 2001
- Arici DS et al: Mullerian adenosarcoma of the uterus associated with tamoxifen therapy. Arch Gynecol Obstet. 264(2):105-7, 2000
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References
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Tables
KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Definitions
- Müllerian adenosarcoma
- Subtype of mixed epithelial-mesenchymal tumors, possibly spectrum with adenosarcoma as intermediate malignant potential
- Adenofibroma: Benign epithelial and mesenchymal components
- Adenosarcoma: Benign epithelial and malignant mesenchymal components
- Carcinosarcoma: Malignant epithelial and mesenchymal components
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Lugo Santiago N et al: Management and survival of patients with mullerian adenosarcoma of the cervix without sarcomatous overgrowth desiring fertility preservation, a case report and review of the literature. Gynecol Oncol Rep. 32:100525, 2020
- Huang YT et al: Current status of magnetic resonance imaging in patients with malignant uterine neoplasms: a review. Korean J Radiol. 20(1):18-33, 2019
- Kudela E et al: Mullerian adenosarcomas of the uterine cervix with sarcomatous overgrowth. Curr Probl Cancer. 43(4):371-6, 2019
- Parra-Herran C et al: Uterine mesenchymal tumors: update on classification, staging, and molecular features. Surg Pathol Clin. 12(2):363-96, 2019
- Vilches Jimenez JC et al: Diagnostic challenges: low-grade adenosarcoma on deep endometriosis. BMC Womens Health. 19(1):124, 2019
- Yuan Z et al: Uterine adenosarcoma: a retrospective 12-year single-center study. Front Oncol. 9:237, 2019
- Nathenson MJ et al: Prognostic factors for uterine adenosarcoma: a review. Expert Rev Anticancer Ther. 18(11):1093-100, 2018
- Nathenson MJ et al: The importance of lymphovascular invasion in uterine adenosarcomas: analysis of clinical, prognostic, and treatment outcomes. Int J Gynecol Cancer. 28(7):1297-310, 2018
- Ulrich UA et al: Uterine adenosarcoma. Oncol Res Treat. 41(11):693-6, 2018
- Nathenson MJ et al: Uterine Adenosarcoma: a review. Curr Oncol Rep. 18(11):68, 2016
- Pinto A et al: Uterine adenosarcoma. Arch Pathol Lab Med. 140(3):286-90, 2016
- Seagle BL et al: Survival of women with mullerian adenosarcoma: a National Cancer Data Base study. Gynecol Oncol. 143(3):636-41, 2016
- Chin PS et al: Diagnosis and management of müllerian adenosarcoma of the uterine cervix. Int J Gynaecol Obstet. 121(3):229-32, 2013
- Hirschowitz L et al: Intravascular adenomyomatosis: expanding the morphologic spectrum of intravascular leiomyomatosis. Am J Surg Pathol. 37(9):1395-400, 2013
- Lee TY et al: Synchronous occurrence of primary malignant mixed müllerian tumor in ovary and uterus. Obstet Gynecol Sci. 56(4):269-72, 2013
- Novetsky AP et al: Management of sarcomas of the uterus. Curr Opin Oncol. 25(5):546-52, 2013
- Sutton G: Uterine sarcomas 2013. Gynecol Oncol. 130(1):3-5, 2013
- Tanner EJ et al: Management of uterine adenosarcomas with and without sarcomatous overgrowth. Gynecol Oncol. 129(1):140-4, 2013
- Tirumani SH et al: Current concepts in the imaging of uterine sarcoma. Abdom Imaging. 38(2):397-411, 2013
- Yu J et al: [Clinicopathologic characteristics of müllerian adenosarcoma of uterus:a comparative analysis of 7 cases before and after surgery.] Zhonghua Bing Li Xue Za Zhi. 42(8):547-8, 2013
- Akhavan A et al: Uterine adenosarcoma in a patient with history of breast cancer and long-term tamoxifen consumption. BMJ Case Rep. 2012, 2012
- Tropé CG et al: Diagnosis and treatment of sarcoma of the uterus. A review. Acta Oncol. 51(6):694-705, 2012
- Sameshima N et al: So-called 'adenosarcoma' of the kidney a novel adult renal tumor with a cystic appearance. Pathol Int. 61(5):313-8, 2011
- Yoshizako T et al: MR imaging of uterine adenosarcoma: case report and literature review. Magn Reson Med Sci. 10(4):251-4, 2011
- Takeuchi M et al: Adenosarcoma of the uterus: magnetic resonance imaging characteristics. Clin Imaging. 33(3):244-7, 2009
- Soh E et al: Magnetic resonance imaging findings of tamoxifen-associated uterine müllerian adenosarcoma: a case report. Acta Radiol. 49(7):848-51, 2008
- Tjalma WA et al: Mullerian adenosarcoma of the uterus associated with long-term oral contraceptive use. Eur J Obstet Gynecol Reprod Biol. 119(2):253-4, 2005
- Crade M et al: Pedicle sign and diagnosis of endometrial adenosarcoma. J Ultrasound Med. 23(9):1217-9, 2004
- Lee EJ et al: Polypoid adenomyomas: sonohysterographic and color Doppler findings with histopathologic correlation. J Ultrasound Med. 23(11):1421-9; quiz 1431, 2004
- Tinar S et al: Adenosarcoma of the uterus: a case report. MedGenMed. 6(1):51, 2004
- Chourmouzi D et al: Sonography and MRI of tamoxifen-associated mullerian adenosarcoma of the uterus. AJR Am J Roentgenol. 181(6):1673-5, 2003
- Rha SE et al: CT and MRI of uterine sarcomas and their mimickers. AJR Am J Roentgenol. 181(5):1369-74, 2003
- Hann LE et al: Sonohysterography for evaluation of the endometrium in women treated with tamoxifen. AJR Am J Roentgenol. 177(2):337-42, 2001
- Krivak TC et al: Uterine adenosarcoma with sarcomatous overgrowth versus uterine carcinosarcoma: comparison of treatment and survival. Gynecol Oncol. 83(1):89-94, 2001
- Arici DS et al: Mullerian adenosarcoma of the uterus associated with tamoxifen therapy. Arch Gynecol Obstet. 264(2):105-7, 2000
