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Uterine and Endometrial Cancers
Brad Perry, MD; Paige Bennett, MD
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      TERMINOLOGY

      • Definitions

        • Endometrial adenocarcinoma
          • Neoplasm of uterine glandular epithelium
          • Most common type of endometrial cancer

      IMAGING

      • MR Findings

        • F-18 FDG PET/CT

          DIFFERENTIAL DIAGNOSIS

            PATHOLOGY

            • General Features

              • Staging, Grading, & Classification

                CLINICAL ISSUES

                • Presentation

                  • Demographics

                    • Natural History & Prognosis

                      • Treatment

                        DIAGNOSTIC CHECKLIST

                        • Consider

                          • Image Interpretation Pearls

                            Selected References

                            1. Oldan JD et al: Applications of PET/MR imaging in urogynecologic and genitourinary cancers. Magn Reson Imaging Clin N Am. 25(2):335-350, 2017
                            2. Meissnitzer M et al: MRI of endometrium cancer - how we do it. Cancer Imaging. 16:11, 2016
                            3. Faria SC et al: Imaging in endometrial carcinoma. Indian J Radiol Imaging. 25(2):137-47, 2015
                            4. Husby JA et al: Metabolic tumor volume on 18F-FDG PET/CT improves preoperative identification of high-risk endometrial carcinoma patients. J Nucl Med. 56(8):1191-8, 2015
                            5. Musto A et al: Role of 18F-FDG PET/CT in the carcinoma of the uterus: a review of literature. Yonsei Med J. 55(6):1467-72, 2014
                            6. Picchio M et al: High-grade endometrial cancer: value of [(18)F]FDG PET/CT in preoperative staging. Nucl Med Commun. 31(6):506-12, 2010
                            7. Kitajima K et al: Accuracy of 18F-FDG PET/CT in detecting pelvic and paraaortic lymph node metastasis in patients with endometrial cancer. AJR Am J Roentgenol. 190(6):1652-8, 2008
                            8. Sironi S et al: Post-therapy surveillance of patients with uterine cancers: value of integrated FDG PET/CT in the detection of recurrence. Eur J Nucl Med Mol Imaging, 2006
                            Related Anatomy
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                            Related Differential Diagnoses
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                            References
                            Tables

                            Tables

                            KEY FACTS

                            • Imaging

                              • Top Differential Diagnoses

                                TERMINOLOGY

                                • Definitions

                                  • Endometrial adenocarcinoma
                                    • Neoplasm of uterine glandular epithelium
                                    • Most common type of endometrial cancer

                                IMAGING

                                • MR Findings

                                  • F-18 FDG PET/CT

                                    DIFFERENTIAL DIAGNOSIS

                                      PATHOLOGY

                                      • General Features

                                        • Staging, Grading, & Classification

                                          CLINICAL ISSUES

                                          • Presentation

                                            • Demographics

                                              • Natural History & Prognosis

                                                • Treatment

                                                  DIAGNOSTIC CHECKLIST

                                                  • Consider

                                                    • Image Interpretation Pearls

                                                      Selected References

                                                      1. Oldan JD et al: Applications of PET/MR imaging in urogynecologic and genitourinary cancers. Magn Reson Imaging Clin N Am. 25(2):335-350, 2017
                                                      2. Meissnitzer M et al: MRI of endometrium cancer - how we do it. Cancer Imaging. 16:11, 2016
                                                      3. Faria SC et al: Imaging in endometrial carcinoma. Indian J Radiol Imaging. 25(2):137-47, 2015
                                                      4. Husby JA et al: Metabolic tumor volume on 18F-FDG PET/CT improves preoperative identification of high-risk endometrial carcinoma patients. J Nucl Med. 56(8):1191-8, 2015
                                                      5. Musto A et al: Role of 18F-FDG PET/CT in the carcinoma of the uterus: a review of literature. Yonsei Med J. 55(6):1467-72, 2014
                                                      6. Picchio M et al: High-grade endometrial cancer: value of [(18)F]FDG PET/CT in preoperative staging. Nucl Med Commun. 31(6):506-12, 2010
                                                      7. Kitajima K et al: Accuracy of 18F-FDG PET/CT in detecting pelvic and paraaortic lymph node metastasis in patients with endometrial cancer. AJR Am J Roentgenol. 190(6):1652-8, 2008
                                                      8. Sironi S et al: Post-therapy surveillance of patients with uterine cancers: value of integrated FDG PET/CT in the detection of recurrence. Eur J Nucl Med Mol Imaging, 2006