Bookmarks
KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
- Malignant mixed müllerian tumor
- Malignant mixed mesodermal tumor
Definitions
- Malignant uterine neoplasm composed of both carcinomatous (epithelial) and sarcomatous (mesenchymal) components
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Bi Q et al: The value of clinical parameters combined with magnetic resonance imaging (MRI) features for preoperatively distinguishing different subtypes of uterine sarcomas: an observational study (STROBE compliant). Medicine (Baltimore). 99(16):e19787, 2020
- Abdulfatah E et al: Predictive histologic factors in carcinosarcomas of the uterus: a multi-institutional study. Int J Gynecol Pathol. 38(3):205-15, 2019
- Cuevas IC et al: Fbxw7 is a driver of uterine carcinosarcoma by promoting epithelial-mesenchymal transition. Proc Natl Acad Sci U S A. 116(51):25880-90, 2019
- Huang YT et al: Current status of magnetic resonance imaging in patients with malignant uterine neoplasms: a review. Korean J Radiol. 20(1):18-33, 2019
- Kurnit KC et al: Prognostic factors impacting survival in early stage uterine carcinosarcoma. Gynecol Oncol. 152(1):31-7, 2019
- Li Y et al: Outcome of adjuvant radiotherapy after total hysterectomy in patients with uterine leiomyosarcoma or carcinosarcoma: a SEER-based study. BMC Cancer. 19(1):697, 2019
- Sagebiel TL et al: Uterine carcinosarcomas. Semin Ultrasound CT MR. 40(4):295-301, 2019
- Denschlag D et al: Uterine carcinosarcomas - diagnosis and management. Oncol Res Treat. 41(11):675-9, 2018
- Jantarasaengaram S et al: Three-dimensional ultrasound with volume contrast imaging for preoperative assessment of myometrial invasion and cervical involvement in women with endometrial cancer. Ultrasound Obstet Gynecol. 43(5):569-74, 2014
- Anupama R et al: Carcinosarcoma of the uterus-a single institution retrospective analysis of the management and outcome and a brief review of literature. Indian J Surg Oncol. 4(3):222-8, 2013
- Guntupalli SR et al: Wilms' tumor 1 protein and estrogen receptor beta expression are associated with poor outcomes in uterine carcinosarcoma. Ann Surg Oncol. 20(7):2373-9, 2013
- Lopez-Chardi L et al: Mesonephric carcinosarcoma of the uterine cervix: a case report. Eur J Gynaecol Oncol. 34(4):336-8, 2013
- Machida H et al: Impact of multimodal therapy on the survival of patients with newly diagnosed uterine carcinosarcoma. Eur J Gynaecol Oncol. 34(4):291-5, 2013
- Pacaut C et al: Uterine and ovary carcinosarcomas: outcome, prognosis factors, and adjuvant therapy. Am J Clin Oncol. 38(3):272-7, 2013
- Rauh-Hain JA et al: Prognostic determinants in patients with uterine and ovarian carcinosarcoma. J Reprod Med. 58(7-8):297-304, 2013
- Saglam O et al: AKT, EGFR, C-ErbB-2, and C-kit expression in uterine carcinosarcoma. Int J Gynecol Pathol. 32(5):493-500, 2013
- Sutton G: Uterine sarcomas 2013. Gynecol Oncol. 130(1):3-5, 2013
- Tasic L et al: Carcinosarcoma of the uterus in advanced stage: a case report. Eur J Gynaecol Oncol. 34(4):343-6, 2013
- Wu YC et al: Intramural metastases of rectum from carcinosarcoma (malignant müllerian mixed tumor) of uterine cervix. Clin Nucl Med. 38(2):137-9, 2013
- Lee EJ et al: Malignant mixed Müllerian tumors of the uterus: sonographic spectrum. Ultrasound Obstet Gynecol. 39(3):348-53, 2012
- Shah SH et al: Uterine sarcomas: then and now. AJR Am J Roentgenol. 199(1):213-23, 2012
- Tropé CG et al: Diagnosis and treatment of sarcoma of the uterus. A review. Acta Oncol. 51(6):694-705, 2012
- Genever AV et al: Can MRI predict the diagnosis of endometrial carcinosarcoma? Clin Radiol. 66(7):621-4, 2011
- Bharwani N et al: MRI appearances of uterine malignant mixed müllerian tumors. AJR Am J Roentgenol. 195(5):1268-75, 2010
- Kato H et al: Carcinosarcoma of the uterus: radiologic-pathologic correlations with magnetic resonance imaging including diffusion-weighted imaging. Magn Reson Imaging. 26(10):1446-50, 2008
- Spaziani E et al: Carcinosarcoma of the uterus: a case report and review of the literature. Eur J Gynaecol Oncol. 29(5):531-4, 2008
- Tanaka YO et al: Carcinosarcoma of the uterus: MR findings. J Magn Reson Imaging. 28(2):434-9, 2008
- Teo SY et al: Primary malignant mixed mullerian tumor of the uterus: findings on sonography, CT, and gadolinium-enhanced MRI. AJR Am J Roentgenol. 191(1):278-83, 2008
- Huang GS et al: Serum CA125 predicts extrauterine disease and survival in uterine carcinosarcoma. Gynecol Oncol. 107(3):513-7, 2007
- Takeuchi M et al: Pathologies of the uterine endometrial cavity: usual and unusual manifestations and pitfalls on magnetic resonance imaging. Eur Radiol. 15(11):2244-55, 2005
- Callister M et al: Malignant mixed Mullerian tumors of the uterus: analysis of patterns of failure, prognostic factors, and treatment outcome. Int J Radiat Oncol Biol Phys. 58(3):786-96, 2004
- Chaudhry S et al: Benign and malignant diseases of the endometrium. Top Magn Reson Imaging. 14(4):339-57, 2003
- Kido A et al: Diffusely enlarged uterus: evaluation with MR imaging. Radiographics. 23(6):1423-39, 2003
- Rha SE et al: CT and MRI of uterine sarcomas and their mimickers. AJR Am J Roentgenol. 181(5):1369-74, 2003
- Szklaruk J et al: MR imaging of common and uncommon large pelvic masses. Radiographics. 23(2):403-24, 2003
- Inthasorn P et al: Analysis of clinicopathologic factors in malignant mixed Mullerian tumors of the uterine corpus. Int J Gynecol Cancer. 12(4):348-53, 2002
- Ohguri T et al: MRI findings including gadolinium-enhanced dynamic studies of malignant, mixed mesodermal tumors of the uterus: differentiation from endometrial carcinomas. Eur Radiol. 12(11):2737-42, 2002
- Sahdev A et al: MR imaging of uterine sarcomas. AJR Am J Roentgenol. 177(6):1307-11, 2001
Related Anatomy
Loading...
Related Differential Diagnoses
Loading...
References
Tables
Tables
KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
- Malignant mixed müllerian tumor
- Malignant mixed mesodermal tumor
Definitions
- Malignant uterine neoplasm composed of both carcinomatous (epithelial) and sarcomatous (mesenchymal) components
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Bi Q et al: The value of clinical parameters combined with magnetic resonance imaging (MRI) features for preoperatively distinguishing different subtypes of uterine sarcomas: an observational study (STROBE compliant). Medicine (Baltimore). 99(16):e19787, 2020
- Abdulfatah E et al: Predictive histologic factors in carcinosarcomas of the uterus: a multi-institutional study. Int J Gynecol Pathol. 38(3):205-15, 2019
- Cuevas IC et al: Fbxw7 is a driver of uterine carcinosarcoma by promoting epithelial-mesenchymal transition. Proc Natl Acad Sci U S A. 116(51):25880-90, 2019
- Huang YT et al: Current status of magnetic resonance imaging in patients with malignant uterine neoplasms: a review. Korean J Radiol. 20(1):18-33, 2019
- Kurnit KC et al: Prognostic factors impacting survival in early stage uterine carcinosarcoma. Gynecol Oncol. 152(1):31-7, 2019
- Li Y et al: Outcome of adjuvant radiotherapy after total hysterectomy in patients with uterine leiomyosarcoma or carcinosarcoma: a SEER-based study. BMC Cancer. 19(1):697, 2019
- Sagebiel TL et al: Uterine carcinosarcomas. Semin Ultrasound CT MR. 40(4):295-301, 2019
- Denschlag D et al: Uterine carcinosarcomas - diagnosis and management. Oncol Res Treat. 41(11):675-9, 2018
- Jantarasaengaram S et al: Three-dimensional ultrasound with volume contrast imaging for preoperative assessment of myometrial invasion and cervical involvement in women with endometrial cancer. Ultrasound Obstet Gynecol. 43(5):569-74, 2014
- Anupama R et al: Carcinosarcoma of the uterus-a single institution retrospective analysis of the management and outcome and a brief review of literature. Indian J Surg Oncol. 4(3):222-8, 2013
- Guntupalli SR et al: Wilms' tumor 1 protein and estrogen receptor beta expression are associated with poor outcomes in uterine carcinosarcoma. Ann Surg Oncol. 20(7):2373-9, 2013
- Lopez-Chardi L et al: Mesonephric carcinosarcoma of the uterine cervix: a case report. Eur J Gynaecol Oncol. 34(4):336-8, 2013
- Machida H et al: Impact of multimodal therapy on the survival of patients with newly diagnosed uterine carcinosarcoma. Eur J Gynaecol Oncol. 34(4):291-5, 2013
- Pacaut C et al: Uterine and ovary carcinosarcomas: outcome, prognosis factors, and adjuvant therapy. Am J Clin Oncol. 38(3):272-7, 2013
- Rauh-Hain JA et al: Prognostic determinants in patients with uterine and ovarian carcinosarcoma. J Reprod Med. 58(7-8):297-304, 2013
- Saglam O et al: AKT, EGFR, C-ErbB-2, and C-kit expression in uterine carcinosarcoma. Int J Gynecol Pathol. 32(5):493-500, 2013
- Sutton G: Uterine sarcomas 2013. Gynecol Oncol. 130(1):3-5, 2013
- Tasic L et al: Carcinosarcoma of the uterus in advanced stage: a case report. Eur J Gynaecol Oncol. 34(4):343-6, 2013
- Wu YC et al: Intramural metastases of rectum from carcinosarcoma (malignant müllerian mixed tumor) of uterine cervix. Clin Nucl Med. 38(2):137-9, 2013
- Lee EJ et al: Malignant mixed Müllerian tumors of the uterus: sonographic spectrum. Ultrasound Obstet Gynecol. 39(3):348-53, 2012
- Shah SH et al: Uterine sarcomas: then and now. AJR Am J Roentgenol. 199(1):213-23, 2012
- Tropé CG et al: Diagnosis and treatment of sarcoma of the uterus. A review. Acta Oncol. 51(6):694-705, 2012
- Genever AV et al: Can MRI predict the diagnosis of endometrial carcinosarcoma? Clin Radiol. 66(7):621-4, 2011
- Bharwani N et al: MRI appearances of uterine malignant mixed müllerian tumors. AJR Am J Roentgenol. 195(5):1268-75, 2010
- Kato H et al: Carcinosarcoma of the uterus: radiologic-pathologic correlations with magnetic resonance imaging including diffusion-weighted imaging. Magn Reson Imaging. 26(10):1446-50, 2008
- Spaziani E et al: Carcinosarcoma of the uterus: a case report and review of the literature. Eur J Gynaecol Oncol. 29(5):531-4, 2008
- Tanaka YO et al: Carcinosarcoma of the uterus: MR findings. J Magn Reson Imaging. 28(2):434-9, 2008
- Teo SY et al: Primary malignant mixed mullerian tumor of the uterus: findings on sonography, CT, and gadolinium-enhanced MRI. AJR Am J Roentgenol. 191(1):278-83, 2008
- Huang GS et al: Serum CA125 predicts extrauterine disease and survival in uterine carcinosarcoma. Gynecol Oncol. 107(3):513-7, 2007
- Takeuchi M et al: Pathologies of the uterine endometrial cavity: usual and unusual manifestations and pitfalls on magnetic resonance imaging. Eur Radiol. 15(11):2244-55, 2005
- Callister M et al: Malignant mixed Mullerian tumors of the uterus: analysis of patterns of failure, prognostic factors, and treatment outcome. Int J Radiat Oncol Biol Phys. 58(3):786-96, 2004
- Chaudhry S et al: Benign and malignant diseases of the endometrium. Top Magn Reson Imaging. 14(4):339-57, 2003
- Kido A et al: Diffusely enlarged uterus: evaluation with MR imaging. Radiographics. 23(6):1423-39, 2003
- Rha SE et al: CT and MRI of uterine sarcomas and their mimickers. AJR Am J Roentgenol. 181(5):1369-74, 2003
- Szklaruk J et al: MR imaging of common and uncommon large pelvic masses. Radiographics. 23(2):403-24, 2003
- Inthasorn P et al: Analysis of clinicopathologic factors in malignant mixed Mullerian tumors of the uterine corpus. Int J Gynecol Cancer. 12(4):348-53, 2002
- Ohguri T et al: MRI findings including gadolinium-enhanced dynamic studies of malignant, mixed mesodermal tumors of the uterus: differentiation from endometrial carcinomas. Eur Radiol. 12(11):2737-42, 2002
- Sahdev A et al: MR imaging of uterine sarcomas. AJR Am J Roentgenol. 177(6):1307-11, 2001
