Malignant smooth muscle tumor of uterus arising from myometrial tissue or smooth muscle of myometrial vessels
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Huang YT et al: Current status of magnetic resonance imaging in patients with malignant uterine neoplasms: a review. Korean J Radiol. 20(1):18-33, 2019
Oh J et al: Ultrasound features of uterine sarcomas. Ultrasound Q. 35(4):376-84, 2019
Sun S et al: How to differentiate uterine leiomyosarcoma from leiomyoma with imaging. Diagn Interv Imaging. 100(10):619-34, 2019
Sato K et al: Clinical application of diffusion-weighted imaging for preoperative differentiation between uterine leiomyoma and leiomyosarcoma. Am J Obstet Gynecol. 210(4):368, 2014
Tirumani SH et al: Current concepts in the imaging of uterine sarcoma. Abdom Imaging. 38(2):397-411, 2013
Shah SH et al: Uterine sarcomas: then and now. AJR Am J Roentgenol. 199(1):213-23, 2012
Qiu LL et al: Sarcomas of abdominal organs: computed tomography and magnetic resonance imaging findings. Semin Ultrasound CT MR. 32(5):405-21, 2011
Wu TI et al: Clinical presentation and diagnosis of uterine sarcoma, including imaging. Best Pract Res Clin Obstet Gynaecol. 25(6):681-9, 2011
Cornfeld D et al: MRI appearance of mesenchymal tumors of the uterus. Eur J Radiol. 74(1):241-9, 2010
Amant F et al: Clinical management of uterine sarcomas. Lancet Oncol. 10(12):1188-98, 2009
Fukunishi H et al: Unsuspected uterine leiomyosarcoma: magnetic resonance imaging findings before and after focused ultrasound surgery. Int J Gynecol Cancer. 17(3):724-8, 2007
Wu TI et al: Prognostic factors and impact of adjuvant chemotherapy for uterine leiomyosarcoma. Gynecol Oncol. 100(1):166-72, 2006
Acharya S et al: Rare uterine cancers. Lancet Oncol. 6(12):961-71, 2005
Livi L et al: Treatment of uterine sarcoma at the Royal Marsden Hospital from 1974 to 1998. Clin Oncol (R Coll Radiol). 16(4):261-8, 2004
Tanaka YO et al: Smooth muscle tumors of uncertain malignant potential and leiomyosarcomas of the uterus: MR findings. J Magn Reson Imaging. 20(6):998-1007, 2004
Cantisani V et al: Vaginal metastasis from uterine leiomyosarcoma. Magnetic resonance imaging features with pathological correlation. J Comput Assist Tomogr. 27(5):805-9, 2003
Kido A et al: Diffusely enlarged uterus: evaluation with MR imaging. Radiographics. 23(6):1423-39, 2003
Rha SE et al: CT and MRI of uterine sarcomas and their mimickers. AJR Am J Roentgenol. 181(5):1369-74, 2003
Szklaruk J et al: MR imaging of common and uncommon large pelvic masses. Radiographics. 23(2):403-24, 2003
Goto A et al: Usefulness of Gd-DTPA contrast-enhanced dynamic MRI and serum determination of LDH and its isozymes in the differential diagnosis of leiomyosarcoma from degenerated leiomyoma of the uterus. Int J Gynecol Cancer. 12(4):354-61, 2002
Ohara N et al: A comparison of MRI findings of uterine leiomyosarcoma before surgery and at recurrence. J Obstet Gynaecol. 22(1):99, 2002
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
Malignant smooth muscle tumor of uterus arising from myometrial tissue or smooth muscle of myometrial vessels
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Huang YT et al: Current status of magnetic resonance imaging in patients with malignant uterine neoplasms: a review. Korean J Radiol. 20(1):18-33, 2019
Oh J et al: Ultrasound features of uterine sarcomas. Ultrasound Q. 35(4):376-84, 2019
Sun S et al: How to differentiate uterine leiomyosarcoma from leiomyoma with imaging. Diagn Interv Imaging. 100(10):619-34, 2019
Sato K et al: Clinical application of diffusion-weighted imaging for preoperative differentiation between uterine leiomyoma and leiomyosarcoma. Am J Obstet Gynecol. 210(4):368, 2014
Tirumani SH et al: Current concepts in the imaging of uterine sarcoma. Abdom Imaging. 38(2):397-411, 2013
Shah SH et al: Uterine sarcomas: then and now. AJR Am J Roentgenol. 199(1):213-23, 2012
Qiu LL et al: Sarcomas of abdominal organs: computed tomography and magnetic resonance imaging findings. Semin Ultrasound CT MR. 32(5):405-21, 2011
Wu TI et al: Clinical presentation and diagnosis of uterine sarcoma, including imaging. Best Pract Res Clin Obstet Gynaecol. 25(6):681-9, 2011
Cornfeld D et al: MRI appearance of mesenchymal tumors of the uterus. Eur J Radiol. 74(1):241-9, 2010
Amant F et al: Clinical management of uterine sarcomas. Lancet Oncol. 10(12):1188-98, 2009
Fukunishi H et al: Unsuspected uterine leiomyosarcoma: magnetic resonance imaging findings before and after focused ultrasound surgery. Int J Gynecol Cancer. 17(3):724-8, 2007
Wu TI et al: Prognostic factors and impact of adjuvant chemotherapy for uterine leiomyosarcoma. Gynecol Oncol. 100(1):166-72, 2006
Acharya S et al: Rare uterine cancers. Lancet Oncol. 6(12):961-71, 2005
Livi L et al: Treatment of uterine sarcoma at the Royal Marsden Hospital from 1974 to 1998. Clin Oncol (R Coll Radiol). 16(4):261-8, 2004
Tanaka YO et al: Smooth muscle tumors of uncertain malignant potential and leiomyosarcomas of the uterus: MR findings. J Magn Reson Imaging. 20(6):998-1007, 2004
Cantisani V et al: Vaginal metastasis from uterine leiomyosarcoma. Magnetic resonance imaging features with pathological correlation. J Comput Assist Tomogr. 27(5):805-9, 2003
Kido A et al: Diffusely enlarged uterus: evaluation with MR imaging. Radiographics. 23(6):1423-39, 2003
Rha SE et al: CT and MRI of uterine sarcomas and their mimickers. AJR Am J Roentgenol. 181(5):1369-74, 2003
Szklaruk J et al: MR imaging of common and uncommon large pelvic masses. Radiographics. 23(2):403-24, 2003
Goto A et al: Usefulness of Gd-DTPA contrast-enhanced dynamic MRI and serum determination of LDH and its isozymes in the differential diagnosis of leiomyosarcoma from degenerated leiomyoma of the uterus. Int J Gynecol Cancer. 12(4):354-61, 2002
Ohara N et al: A comparison of MRI findings of uterine leiomyosarcoma before surgery and at recurrence. J Obstet Gynaecol. 22(1):99, 2002
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