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Varicella
Janice L. B. Byrne, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Varicella-zoster virus (VZV)
            • Synonyms

              • Fetal varicella syndrome/embryopathy
            • Definitions

              • Transplacental infection of fetus following maternal chickenpox infection
                • Highest risk when acquired at 8- to 20-weeks gestation

            IMAGING

            • Ultrasonographic Findings

              • Imaging Recommendations

                DIFFERENTIAL DIAGNOSIS

                  PATHOLOGY

                  • General Features

                    CLINICAL ISSUES

                    • Presentation

                      • Demographics

                        • Natural History & Prognosis

                          • Treatment

                            Selected References

                            1. Tourtelot E et al: Women who received varicella vaccine versus natural infection have different long-term T cell immunity but similar antibody levels. Vaccine. 38(7):1581-5, 2020
                            2. Gupta V et al: Unusual cause of brachial palsy with diaphragmatic palsy. BMJ Case Rep. 2018
                            3. Hayward K et al: Management of herpes zoster (shingles) during pregnancy. J Obstet Gynaecol. 38(7):887-94, 2018
                            4. Shrim A et al: No. 274-management of varicella infection (chickenpox) in pregnancy. J Obstet Gynaecol Can. 40(8):e652-7, 2018
                            5. Trotta M et al: Epidemiology, management and outcome of varicella in pregnancy: a 20-year experience at the Tuscany Reference Centre for Infectious Diseases in Pregnancy. Infection. 46(5):693-9, 2018
                            6. Mandelbrot L: Fetal varicella - diagnosis, management, and outcome. Prenat Diagn. 32(6):511-8, 2012
                            7. Tongsong T et al: Prenatal sonographic diagnosis of congenital varicella syndrome. J Clin Ultrasound. 40(3):176-8, 2012
                            8. Lamont RF et al: Varicella-zoster virus (chickenpox) infection in pregnancy. BJOG. 118(10):1155-62, 2011
                            9. Sanchez MA et al: The prevalence of congenital varicella syndrome after a maternal infection, but before 20 weeks of pregnancy: a prospective cohort study. J Matern Fetal Neonatal Med. 24(2):341-7, 2011
                            10. Auriti C et al: Congenital varicella syndrome: still a problem? Fetal Diagn Ther. 25(2):224-9, 2009
                            11. Smith CK et al: Varicella in the fetus and newborn. Semin Fetal Neonatal Med. 14(4):209-17, 2009
                            12. Meyberg-Solomayer GC et al: Prenatal ultrasound diagnosis, follow-up, and outcome of congenital varicella syndrome. Fetal Diagn Ther. 21(3):296-301, 2006
                            13. Tan MP et al: Chickenpox in pregnancy: revisited. Reprod Toxicol. 21(4):410-20, 2006
                            14. Verstraelen H et al: Prenatal ultrasound and magnetic resonance imaging in fetal varicella syndrome: correlation with pathology findings. Prenat Diagn. 23(9):705-9, 2003
                            Related Anatomy
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                            Related Differential Diagnoses
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                            References
                            Tables

                            Tables

                            KEY FACTS

                            • Terminology

                              • Imaging

                                • Top Differential Diagnoses

                                  • Pathology

                                    • Clinical Issues

                                      TERMINOLOGY

                                      • Abbreviations

                                        • Varicella-zoster virus (VZV)
                                      • Synonyms

                                        • Fetal varicella syndrome/embryopathy
                                      • Definitions

                                        • Transplacental infection of fetus following maternal chickenpox infection
                                          • Highest risk when acquired at 8- to 20-weeks gestation

                                      IMAGING

                                      • Ultrasonographic Findings

                                        • Imaging Recommendations

                                          DIFFERENTIAL DIAGNOSIS

                                            PATHOLOGY

                                            • General Features

                                              CLINICAL ISSUES

                                              • Presentation

                                                • Demographics

                                                  • Natural History & Prognosis

                                                    • Treatment

                                                      Selected References

                                                      1. Tourtelot E et al: Women who received varicella vaccine versus natural infection have different long-term T cell immunity but similar antibody levels. Vaccine. 38(7):1581-5, 2020
                                                      2. Gupta V et al: Unusual cause of brachial palsy with diaphragmatic palsy. BMJ Case Rep. 2018
                                                      3. Hayward K et al: Management of herpes zoster (shingles) during pregnancy. J Obstet Gynaecol. 38(7):887-94, 2018
                                                      4. Shrim A et al: No. 274-management of varicella infection (chickenpox) in pregnancy. J Obstet Gynaecol Can. 40(8):e652-7, 2018
                                                      5. Trotta M et al: Epidemiology, management and outcome of varicella in pregnancy: a 20-year experience at the Tuscany Reference Centre for Infectious Diseases in Pregnancy. Infection. 46(5):693-9, 2018
                                                      6. Mandelbrot L: Fetal varicella - diagnosis, management, and outcome. Prenat Diagn. 32(6):511-8, 2012
                                                      7. Tongsong T et al: Prenatal sonographic diagnosis of congenital varicella syndrome. J Clin Ultrasound. 40(3):176-8, 2012
                                                      8. Lamont RF et al: Varicella-zoster virus (chickenpox) infection in pregnancy. BJOG. 118(10):1155-62, 2011
                                                      9. Sanchez MA et al: The prevalence of congenital varicella syndrome after a maternal infection, but before 20 weeks of pregnancy: a prospective cohort study. J Matern Fetal Neonatal Med. 24(2):341-7, 2011
                                                      10. Auriti C et al: Congenital varicella syndrome: still a problem? Fetal Diagn Ther. 25(2):224-9, 2009
                                                      11. Smith CK et al: Varicella in the fetus and newborn. Semin Fetal Neonatal Med. 14(4):209-17, 2009
                                                      12. Meyberg-Solomayer GC et al: Prenatal ultrasound diagnosis, follow-up, and outcome of congenital varicella syndrome. Fetal Diagn Ther. 21(3):296-301, 2006
                                                      13. Tan MP et al: Chickenpox in pregnancy: revisited. Reprod Toxicol. 21(4):410-20, 2006
                                                      14. Verstraelen H et al: Prenatal ultrasound and magnetic resonance imaging in fetal varicella syndrome: correlation with pathology findings. Prenat Diagn. 23(9):705-9, 2003