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Vascular Graft Infection
James Patrick Davidson, MD; Paige Bennett, MD
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KEY FACTS

  • Imaging

    • Diagnostic Checklist

      TERMINOLOGY

      • Definitions

        • Common vascular grafts: Aortic or aortoiliac for aneurysm repair, peripheral grafts for dialysis access or peripheral arterial disease
          • Infected graft: Inflammatory change, phlegmon or abscess associated with bacterial ingrowth into or around vascular graft
          • Colonized graft: Bacteria living on graft without frank inflammation or invasion
          • Graft incorporation: Ingrowth of normal host cells into vascular graft creating pseudoendothelium
          • Graft disincorporation: Loss of host pseudoendothelium resulting in areas of bare graft

      IMAGING

      • General Features

        • Nuclear Medicine Findings

          • Imaging Recommendations

            DIFFERENTIAL DIAGNOSIS

              PATHOLOGY

              • Gross Pathologic & Surgical Features

                • Microscopic Features

                  CLINICAL ISSUES

                  • Presentation

                    • Natural History & Prognosis

                      • Treatment

                        DIAGNOSTIC CHECKLIST

                        • Consider

                          • Image Interpretation Pearls

                            Selected References

                            1. Husmann L et al: Comparing diagnostic accuracy of 18F-FDG-PET/CT, contrast enhanced CT and combined imaging in patients with suspected vascular graft infections. Eur J Nucl Med Mol Imaging. 46(6):1359-68, 2019
                            2. Rojoa D et al: 18F-FDG PET in the diagnosis of vascular prosthetic graft infection: A diagnostic test accuracy meta-analysis. Eur J Vasc Endovasc Surg. 57(2):292-301, 2019
                            3. Sah BR et al: Diagnostic performance of 18F-FDG-PET/CT in vascular graft infections. Eur J Vasc Endovasc Surg. 49(4):455-64, 2015
                            4. Saleem BR et al: 18F-Fluorodeoxyglucose positron emission tomography/CT scanning in diagnosing vascular prosthetic graft infection. Biomed Res Int. 2014:471971, 2014
                            5. Keidar Z et al: FDG-PET in prosthetic graft infections. Semin Nucl Med. 43(5):396-402, 2013
                            Related Anatomy
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                            Related Differential Diagnoses
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                            References
                            Tables

                            Tables

                            KEY FACTS

                            • Imaging

                              • Diagnostic Checklist

                                TERMINOLOGY

                                • Definitions

                                  • Common vascular grafts: Aortic or aortoiliac for aneurysm repair, peripheral grafts for dialysis access or peripheral arterial disease
                                    • Infected graft: Inflammatory change, phlegmon or abscess associated with bacterial ingrowth into or around vascular graft
                                    • Colonized graft: Bacteria living on graft without frank inflammation or invasion
                                    • Graft incorporation: Ingrowth of normal host cells into vascular graft creating pseudoendothelium
                                    • Graft disincorporation: Loss of host pseudoendothelium resulting in areas of bare graft

                                IMAGING

                                • General Features

                                  • Nuclear Medicine Findings

                                    • Imaging Recommendations

                                      DIFFERENTIAL DIAGNOSIS

                                        PATHOLOGY

                                        • Gross Pathologic & Surgical Features

                                          • Microscopic Features

                                            CLINICAL ISSUES

                                            • Presentation

                                              • Natural History & Prognosis

                                                • Treatment

                                                  DIAGNOSTIC CHECKLIST

                                                  • Consider

                                                    • Image Interpretation Pearls

                                                      Selected References

                                                      1. Husmann L et al: Comparing diagnostic accuracy of 18F-FDG-PET/CT, contrast enhanced CT and combined imaging in patients with suspected vascular graft infections. Eur J Nucl Med Mol Imaging. 46(6):1359-68, 2019
                                                      2. Rojoa D et al: 18F-FDG PET in the diagnosis of vascular prosthetic graft infection: A diagnostic test accuracy meta-analysis. Eur J Vasc Endovasc Surg. 57(2):292-301, 2019
                                                      3. Sah BR et al: Diagnostic performance of 18F-FDG-PET/CT in vascular graft infections. Eur J Vasc Endovasc Surg. 49(4):455-64, 2015
                                                      4. Saleem BR et al: 18F-Fluorodeoxyglucose positron emission tomography/CT scanning in diagnosing vascular prosthetic graft infection. Biomed Res Int. 2014:471971, 2014
                                                      5. Keidar Z et al: FDG-PET in prosthetic graft infections. Semin Nucl Med. 43(5):396-402, 2013