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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Abbreviations
- Hepatic venoocclusive disease (VOD)
Synonyms
- Hepatic sinusoidal obstruction syndrome (preferred)
Definitions
- Hepatic venous outflow obstruction due to occlusion of terminal hepatic venules and sinusoids
IMAGING
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Chan SS et al: Imaging in hepatic veno-occlusive disease/sinusoidal obstruction syndrome. Biol Blood Marrow Transplant. 26(10):1770-9, 2020
- Elsayes KM et al: A comprehensive approach to hepatic vascular disease. Radiographics. 37(3):813-6, 2017
- Li X et al: Magnetic Resonance imaging findings in patients with pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome. Clin Gastroenterol Hepatol. 15(6):955-7, 2017
- Yakushijin K et al: Sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation: incidence, risk factors and outcomes. Bone Marrow Transplant. 51(3):403-9, 2016
- Gao H et al: Definitive diagnosis of hepatic sinusoidal obstruction syndrome induced by pyrrolizidine alkaloids. J Dig Dis. 13(1):33-9, 2012
- Jevtic D et al: Veno-occlusive disease in pediatric patients after hematopoietic stem cell transplantation: relevance of activated coagulation and fibrinolysis markers and natural anticoagulants. J Pediatr Hematol Oncol. 33(3):227-34, 2011
- Lin G et al: Hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum. J Hepatol. 54(4):666-73, 2011
- Mahgerefteh SY et al: Radiologic imaging and intervention for gastrointestinal and hepatic complications of hematopoietic stem cell transplantation. Radiology. 258(3):660-71, 2011
- Menke J: Education and imaging. Hepatobiliary and pancreatic: sinusoidal obstruction syndrome during chemotherapy. J Gastroenterol Hepatol. 26(6):1083, 2011
- Sanei MH et al: Acute cellular rejection resulting in sinusoidal obstruction syndrome and ascites postliver transplantation. Transplantation. 92(10):1152-8, 2011
- Sebagh M et al: Significance of isolated hepatic veno-occlusive disease/sinusoidal obstruction syndrome after liver transplantation. Liver Transpl. 17(7):798-808, 2011
- Rubbia-Brandt L: Sinusoidal obstruction syndrome. Clin Liver Dis. 14(4):651-68, 2010
- Song MK et al: Hepatic artery resistance index at doppler ultrasonography is a useful parameter of hepatic graft-vs-host disease after allogeneic stem cell transplantation. Transplant Proc. 42(9):3717-22, 2010
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Abbreviations
- Hepatic venoocclusive disease (VOD)
Synonyms
- Hepatic sinusoidal obstruction syndrome (preferred)
Definitions
- Hepatic venous outflow obstruction due to occlusion of terminal hepatic venules and sinusoids
IMAGING
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Chan SS et al: Imaging in hepatic veno-occlusive disease/sinusoidal obstruction syndrome. Biol Blood Marrow Transplant. 26(10):1770-9, 2020
- Elsayes KM et al: A comprehensive approach to hepatic vascular disease. Radiographics. 37(3):813-6, 2017
- Li X et al: Magnetic Resonance imaging findings in patients with pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome. Clin Gastroenterol Hepatol. 15(6):955-7, 2017
- Yakushijin K et al: Sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation: incidence, risk factors and outcomes. Bone Marrow Transplant. 51(3):403-9, 2016
- Gao H et al: Definitive diagnosis of hepatic sinusoidal obstruction syndrome induced by pyrrolizidine alkaloids. J Dig Dis. 13(1):33-9, 2012
- Jevtic D et al: Veno-occlusive disease in pediatric patients after hematopoietic stem cell transplantation: relevance of activated coagulation and fibrinolysis markers and natural anticoagulants. J Pediatr Hematol Oncol. 33(3):227-34, 2011
- Lin G et al: Hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum. J Hepatol. 54(4):666-73, 2011
- Mahgerefteh SY et al: Radiologic imaging and intervention for gastrointestinal and hepatic complications of hematopoietic stem cell transplantation. Radiology. 258(3):660-71, 2011
- Menke J: Education and imaging. Hepatobiliary and pancreatic: sinusoidal obstruction syndrome during chemotherapy. J Gastroenterol Hepatol. 26(6):1083, 2011
- Sanei MH et al: Acute cellular rejection resulting in sinusoidal obstruction syndrome and ascites postliver transplantation. Transplantation. 92(10):1152-8, 2011
- Sebagh M et al: Significance of isolated hepatic veno-occlusive disease/sinusoidal obstruction syndrome after liver transplantation. Liver Transpl. 17(7):798-808, 2011
- Rubbia-Brandt L: Sinusoidal obstruction syndrome. Clin Liver Dis. 14(4):651-68, 2010
- Song MK et al: Hepatic artery resistance index at doppler ultrasonography is a useful parameter of hepatic graft-vs-host disease after allogeneic stem cell transplantation. Transplant Proc. 42(9):3717-22, 2010
