Claudio Silva, MD, MSc, MBA; Brett W. Carter, MD, CPPS
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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
Dystrophic calcification
Metastatic calcification
Definitions
Dystrophic calcification
Sequela of local tissue damage &/or cellular necrosis leading to calcification
Normal serum calcium and phosphorus levels
Most prevalent myocardial calcification: Previous myocardial infarction (MI) leading to myocyte necrosis
Metastatic calcification
Sequela of systemic process (e.g., abnormalities of calcium homeostasis)
Elevated calcium or parathyroid hormone levels
May occur in normal tissue
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Demographics
Natural History & Prognosis
Treatment
Selected References
Ahmed T et al: Myocardial calcification secondary to toxic shock syndrome: a comparative review of 17 cases. BMJ Case Rep. 12(1), 2019
Alyesh DM et al: Postinfarction myocardial calcifications on cardiac computed tomography: implications for mapping and ablation in patients with nontolerated ventricular tachycardias. Circ Arrhythm Electrophysiol. 12(5):e007023, 2019
Nance JW Jr et al: Myocardial calcifications: pathophysiology, etiologies, differential diagnoses, and imaging findings. J Cardiovasc Comput Tomogr. 9(1):58-67, 2015
Abramowitz Y et al: Mitral annulus calcification. J Am Coll Cardiol. 66(17):1934-41, 2015
Ferguson EC et al: Cardiac and pericardial calcifications on chest radiographs. Clin Radiol. 65(9):685-94, 2010
Gowda RM et al: Calcifications of the heart. Radiol Clin North Am. 42(3):603-17, vi-vii, 2004
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
Dystrophic calcification
Metastatic calcification
Definitions
Dystrophic calcification
Sequela of local tissue damage &/or cellular necrosis leading to calcification
Normal serum calcium and phosphorus levels
Most prevalent myocardial calcification: Previous myocardial infarction (MI) leading to myocyte necrosis
Metastatic calcification
Sequela of systemic process (e.g., abnormalities of calcium homeostasis)
Elevated calcium or parathyroid hormone levels
May occur in normal tissue
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Demographics
Natural History & Prognosis
Treatment
Selected References
Ahmed T et al: Myocardial calcification secondary to toxic shock syndrome: a comparative review of 17 cases. BMJ Case Rep. 12(1), 2019
Alyesh DM et al: Postinfarction myocardial calcifications on cardiac computed tomography: implications for mapping and ablation in patients with nontolerated ventricular tachycardias. Circ Arrhythm Electrophysiol. 12(5):e007023, 2019
Nance JW Jr et al: Myocardial calcifications: pathophysiology, etiologies, differential diagnoses, and imaging findings. J Cardiovasc Comput Tomogr. 9(1):58-67, 2015
Abramowitz Y et al: Mitral annulus calcification. J Am Coll Cardiol. 66(17):1934-41, 2015
Ferguson EC et al: Cardiac and pericardial calcifications on chest radiographs. Clin Radiol. 65(9):685-94, 2010
Gowda RM et al: Calcifications of the heart. Radiol Clin North Am. 42(3):603-17, vi-vii, 2004
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