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Gastrointestinal
Diagnosis
Esophagus
Infection
Viral Esophagitis
Viral Esophagitis
Atif Zaheer, MD; Michael P. Federle, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Definitions

                • Inflammation of esophagus of viral etiology
                  • Common: HSV, CMV, HIV
                  • Other: Varicella-zoster virus (VZV), Ebstein-Barr virus (EBV), human papillomavirus (HPV)

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    • Image Interpretation Pearls

                                      Selected References

                                      1. Ullah W et al: Herpes simplex esophagitis in immunocompetent patients: a rare but easily managed condition. S D Med. 72(8):344-7, 2019
                                      2. Hoversten P et al: Infections of the esophagus: an update on risk factors, diagnosis, and management. Dis Esophagus. 31(12), 2018
                                      3. Carucci LR et al: Dysphagia revisited: common and unusual causes. Radiographics. 35(1):105-22, 2015
                                      4. Joo YB et al: Cytomegalovirus esophagitis presents as chest pain in a renal transplant recipient. Korean J Intern Med. 28(4):497-9, 2013
                                      5. Mohiuddin MK et al: Role of Human papilloma virus infection and altered methylation of specific genes in esophageal cancer. Asian Pac J Cancer Prev. 14(7):4187-93, 2013
                                      6. Lavery EA et al: Herpes simplex virus and the alimentary tract. Curr Gastroenterol Rep. 10(4):417-23, 2008
                                      7. Levine MS et al: Diseases of the esophagus: diagnosis with esophagography. Radiology. 237(2):414-27, 2005
                                      8. Mosca S et al: Squamous papilloma of the esophagus: long-term follow up. J Gastroenterol Hepatol. 16(8):857-61, 2001
                                      9. Berkovich GY et al: CT findings in patients with esophagitis. AJR Am J Roentgenol. 175(5):1431-4, 2000
                                      10. Gore R et al: Textbook of Gastrointestinal Radiology. 2nd ed. W.B. Saunders. 1980-92, 2000
                                      11. Fenoglio-Preiser CM: Gastrointestinal pathology: An atlas and text. 2nd ed. Lippincott-Raven. 62-5, 1999
                                      12. Laine L et al: Esophageal disease in human immunodeficiency virus infection. Arch Intern Med. 154(14): 1577-82, 1994
                                      13. Wilcox CM et al: Esophageal infections: etiology, diagnosis, and management. Gastroenterologist. 2(3): 188-206, 1994
                                      14. Levine MS: Radiology of esophagitis: a pattern approach. Radiology. 179(1): 1-7, 1991
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Pathology

                                              • Clinical Issues

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Definitions

                                                    • Inflammation of esophagus of viral etiology
                                                      • Common: HSV, CMV, HIV
                                                      • Other: Varicella-zoster virus (VZV), Ebstein-Barr virus (EBV), human papillomavirus (HPV)

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            • Gross Pathologic & Surgical Features

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Demographics

                                                                  • Natural History & Prognosis

                                                                    • Treatment

                                                                      DIAGNOSTIC CHECKLIST

                                                                      • Consider

                                                                        • Image Interpretation Pearls

                                                                          Selected References

                                                                          1. Ullah W et al: Herpes simplex esophagitis in immunocompetent patients: a rare but easily managed condition. S D Med. 72(8):344-7, 2019
                                                                          2. Hoversten P et al: Infections of the esophagus: an update on risk factors, diagnosis, and management. Dis Esophagus. 31(12), 2018
                                                                          3. Carucci LR et al: Dysphagia revisited: common and unusual causes. Radiographics. 35(1):105-22, 2015
                                                                          4. Joo YB et al: Cytomegalovirus esophagitis presents as chest pain in a renal transplant recipient. Korean J Intern Med. 28(4):497-9, 2013
                                                                          5. Mohiuddin MK et al: Role of Human papilloma virus infection and altered methylation of specific genes in esophageal cancer. Asian Pac J Cancer Prev. 14(7):4187-93, 2013
                                                                          6. Lavery EA et al: Herpes simplex virus and the alimentary tract. Curr Gastroenterol Rep. 10(4):417-23, 2008
                                                                          7. Levine MS et al: Diseases of the esophagus: diagnosis with esophagography. Radiology. 237(2):414-27, 2005
                                                                          8. Mosca S et al: Squamous papilloma of the esophagus: long-term follow up. J Gastroenterol Hepatol. 16(8):857-61, 2001
                                                                          9. Berkovich GY et al: CT findings in patients with esophagitis. AJR Am J Roentgenol. 175(5):1431-4, 2000
                                                                          10. Gore R et al: Textbook of Gastrointestinal Radiology. 2nd ed. W.B. Saunders. 1980-92, 2000
                                                                          11. Fenoglio-Preiser CM: Gastrointestinal pathology: An atlas and text. 2nd ed. Lippincott-Raven. 62-5, 1999
                                                                          12. Laine L et al: Esophageal disease in human immunodeficiency virus infection. Arch Intern Med. 154(14): 1577-82, 1994
                                                                          13. Wilcox CM et al: Esophageal infections: etiology, diagnosis, and management. Gastroenterologist. 2(3): 188-206, 1994
                                                                          14. Levine MS: Radiology of esophagitis: a pattern approach. Radiology. 179(1): 1-7, 1991