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Vitamin A: Complications
B.J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          TERMINOLOGY

          • Definitions

            • Musculoskeletal abnormalities associated with hypervitaminosis A

          IMAGING

          • Radiographic Findings

            DIFFERENTIAL DIAGNOSIS

              PATHOLOGY

              • General Features

                CLINICAL ISSUES

                • Presentation

                  Selected References

                  1. Henning P et al: Retinoid receptors in bone and their role in bone remodeling. Front Endocrinol (Lausanne). 6:31, 2015
                  2. Manickavasagar B et al: Hypervitaminosis A is prevalent in children with CKD and contributes to hypercalcemia. Pediatr Nephrol. 30(2):317-25, 2015
                  3. Yorgan TA et al: Immediate effects of retinoic acid on gene expression in primary murine osteoblasts. J Bone Miner Metab. ePub, 2015
                  4. Sidhu HS et al: Imaging features of therapeutic drug-induced musculoskeletal abnormalities. Radiographics. 32(1):105-27, 2012
                  5. Chroni E et al: Neuromuscular adverse effects associated with systemic retinoid dermatotherapy: monitoring and treatment algorithm for clinicians. Drug Saf. 33(1):25-34, 2010
                  6. Rothenberg AB et al: Hypervitaminosis A-induced premature closure of epiphyses (physeal obliteration) in humans and calves (hyena disease): a historical review of the human and veterinary literature. Pediatr Radiol. 37(12):1264-7, 2007
                  7. Castaño G et al: Vitamin A toxicity in a physical culturist patient: a case report and review of the literature. Ann Hepatol. 5(4):293-395, 2006
                  8. Penniston KL et al: The acute and chronic toxic effects of vitamin A. Am J Clin Nutr. 83(2):191-201, 2006
                  Related Anatomy
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                  Related Differential Diagnoses
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                  References
                  Tables

                  Tables

                  KEY FACTS

                  • Terminology

                    • Imaging

                      • Top Differential Diagnoses

                        • Pathology

                          TERMINOLOGY

                          • Definitions

                            • Musculoskeletal abnormalities associated with hypervitaminosis A

                          IMAGING

                          • Radiographic Findings

                            DIFFERENTIAL DIAGNOSIS

                              PATHOLOGY

                              • General Features

                                CLINICAL ISSUES

                                • Presentation

                                  Selected References

                                  1. Henning P et al: Retinoid receptors in bone and their role in bone remodeling. Front Endocrinol (Lausanne). 6:31, 2015
                                  2. Manickavasagar B et al: Hypervitaminosis A is prevalent in children with CKD and contributes to hypercalcemia. Pediatr Nephrol. 30(2):317-25, 2015
                                  3. Yorgan TA et al: Immediate effects of retinoic acid on gene expression in primary murine osteoblasts. J Bone Miner Metab. ePub, 2015
                                  4. Sidhu HS et al: Imaging features of therapeutic drug-induced musculoskeletal abnormalities. Radiographics. 32(1):105-27, 2012
                                  5. Chroni E et al: Neuromuscular adverse effects associated with systemic retinoid dermatotherapy: monitoring and treatment algorithm for clinicians. Drug Saf. 33(1):25-34, 2010
                                  6. Rothenberg AB et al: Hypervitaminosis A-induced premature closure of epiphyses (physeal obliteration) in humans and calves (hyena disease): a historical review of the human and veterinary literature. Pediatr Radiol. 37(12):1264-7, 2007
                                  7. Castaño G et al: Vitamin A toxicity in a physical culturist patient: a case report and review of the literature. Ann Hepatol. 5(4):293-395, 2006
                                  8. Penniston KL et al: The acute and chronic toxic effects of vitamin A. Am J Clin Nutr. 83(2):191-201, 2006