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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Wegener granulomatosis (WG)
Synonyms
- Granulomatous polyangiitis, granulomatosis with polyangiitis (newly accepted name for WG)
Definitions
- Multisystemic necrotizing granulomatous vasculitis of small to medium vessels without associated infection
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Kallenberg CG: Pathogenesis of ANCA-associated vasculitides. Ann Rheum Dis. 70 Suppl 1:i59-63, 2011
- Langford CA: Cyclophosphamide as induction therapy for Wegener's granulomatosis and microscopic polyangiitis. Clin Exp Immunol. 164 Suppl 1:31-4, 2011
- Niles J: Rituximab in induction therapy for anti-neutrophil cytoplasmic antibody (ANCA) vasculitis. Clin Exp Immunol. 164 Suppl 1:27-30, 2011
- Schilder AM: Wegener's Granulomatosis vasculitis and granuloma. Autoimmun Rev. 9(7):483-7, 2010
- Ananthakrishnan L et al: Wegener's granulomatosis in the chest: high-resolution CT findings. AJR Am J Roentgenol. 192(3):676-82, 2009
- Carruthers D et al: Evidence-based management of ANCA vasculitis. Best Pract Res Clin Rheumatol. 23(3):367-78, 2009
- Grenier PA et al: Nonneoplastic tracheal and bronchial stenoses. Radiol Clin North Am. 47(2):243-60, 2009
- Turnbull J et al: Adverse effects of therapy for ANCA-associated vasculitis. Best Pract Res Clin Rheumatol. 23(3):391-401, 2009
- Jagiello P et al: Complex genetics of Wegener granulomatosis. Autoimmun Rev. 4(1):42-7, 2005
- Daum TE et al: Tracheobronchial involvement in Wegener's granulomatosis. Am J Respir Crit Care Med. 151(2 Pt 1):522-6, 1995
- Hoffman GS et al: Wegener granulomatosis: an analysis of 158 patients. Ann Intern Med. 116(6):488-98, 1992
- Aberle DR et al: Thoracic manifestations of Wegener granulomatosis: diagnosis and course. Radiology. 174(3 Pt 1):703-9, 1990
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References
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Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Wegener granulomatosis (WG)
Synonyms
- Granulomatous polyangiitis, granulomatosis with polyangiitis (newly accepted name for WG)
Definitions
- Multisystemic necrotizing granulomatous vasculitis of small to medium vessels without associated infection
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Kallenberg CG: Pathogenesis of ANCA-associated vasculitides. Ann Rheum Dis. 70 Suppl 1:i59-63, 2011
- Langford CA: Cyclophosphamide as induction therapy for Wegener's granulomatosis and microscopic polyangiitis. Clin Exp Immunol. 164 Suppl 1:31-4, 2011
- Niles J: Rituximab in induction therapy for anti-neutrophil cytoplasmic antibody (ANCA) vasculitis. Clin Exp Immunol. 164 Suppl 1:27-30, 2011
- Schilder AM: Wegener's Granulomatosis vasculitis and granuloma. Autoimmun Rev. 9(7):483-7, 2010
- Ananthakrishnan L et al: Wegener's granulomatosis in the chest: high-resolution CT findings. AJR Am J Roentgenol. 192(3):676-82, 2009
- Carruthers D et al: Evidence-based management of ANCA vasculitis. Best Pract Res Clin Rheumatol. 23(3):367-78, 2009
- Grenier PA et al: Nonneoplastic tracheal and bronchial stenoses. Radiol Clin North Am. 47(2):243-60, 2009
- Turnbull J et al: Adverse effects of therapy for ANCA-associated vasculitis. Best Pract Res Clin Rheumatol. 23(3):391-401, 2009
- Jagiello P et al: Complex genetics of Wegener granulomatosis. Autoimmun Rev. 4(1):42-7, 2005
- Daum TE et al: Tracheobronchial involvement in Wegener's granulomatosis. Am J Respir Crit Care Med. 151(2 Pt 1):522-6, 1995
- Hoffman GS et al: Wegener granulomatosis: an analysis of 158 patients. Ann Intern Med. 116(6):488-98, 1992
- Aberle DR et al: Thoracic manifestations of Wegener granulomatosis: diagnosis and course. Radiology. 174(3 Pt 1):703-9, 1990
