Rare systemic disease caused by Tropheryma whipplei infection leading to multiple systemic manifestations, including chronic diarrhea and malabsorption
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Aguiar Ferreira A et al: Whipple's disease: imaging contribution for a challenging case. BMJ Case Rep. 13(2), 2020
Antunes C et al: Whipple Disease 2020
Nay J et al: Gastrointestinal manifestations of systemic disease: a multimodality review. Abdom Imaging. 40(6):1926-43, 2014
Schwartzman S et al: Whipple's disease. Rheum Dis Clin North Am. 39(2):313-21, 2013
Afshar P et al: Whipple's disease: a rare disease revisited. Curr Gastroenterol Rep. 12(4):263-9, 2010
Freeman HJ: Tropheryma whipplei infection. World J Gastroenterol. 15(17):2078-80, 2009
Iqbal T et al: Whipple's disease with constrictive pericarditis: a rare disease with a rare presentation. Can J Cardiol. 25(3):e89-91, 2009
Martinetti M et al: The HLA alleles DRB1*13 and DQB1*06 are associated to Whipple's disease. Gastroenterology. 136(7):2289-94, 2009
Sanavro SM et al: Whipple's disease: easily diagnosed, if considered. Neth J Med. 67(3):108, 2009
Herlinger H et al: Whipple disease malabsorption states. In Herlinger H et al eds. Clinical Imaging of the Small Intestine. 2nd ed. Springer-Verlag; 1999: 357-9
Horton KM et al: Uncommon inflammatory diseases of the small bowel: CT findings. AJR Am J Roentgenol. 170(2):385-8, 1998
Rubesin SE et al: Small bowel malabsorption: clinical and radiologic perspectives. How we see it. Radiology. 184(2):297-305, 1992
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
Intestinal lipodystrophy
Definitions
Rare systemic disease caused by Tropheryma whipplei infection leading to multiple systemic manifestations, including chronic diarrhea and malabsorption
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Aguiar Ferreira A et al: Whipple's disease: imaging contribution for a challenging case. BMJ Case Rep. 13(2), 2020
Antunes C et al: Whipple Disease 2020
Nay J et al: Gastrointestinal manifestations of systemic disease: a multimodality review. Abdom Imaging. 40(6):1926-43, 2014
Schwartzman S et al: Whipple's disease. Rheum Dis Clin North Am. 39(2):313-21, 2013
Afshar P et al: Whipple's disease: a rare disease revisited. Curr Gastroenterol Rep. 12(4):263-9, 2010
Freeman HJ: Tropheryma whipplei infection. World J Gastroenterol. 15(17):2078-80, 2009
Iqbal T et al: Whipple's disease with constrictive pericarditis: a rare disease with a rare presentation. Can J Cardiol. 25(3):e89-91, 2009
Martinetti M et al: The HLA alleles DRB1*13 and DQB1*06 are associated to Whipple's disease. Gastroenterology. 136(7):2289-94, 2009
Sanavro SM et al: Whipple's disease: easily diagnosed, if considered. Neth J Med. 67(3):108, 2009
Herlinger H et al: Whipple disease malabsorption states. In Herlinger H et al eds. Clinical Imaging of the Small Intestine. 2nd ed. Springer-Verlag; 1999: 357-9
Horton KM et al: Uncommon inflammatory diseases of the small bowel: CT findings. AJR Am J Roentgenol. 170(2):385-8, 1998
Rubesin SE et al: Small bowel malabsorption: clinical and radiologic perspectives. How we see it. Radiology. 184(2):297-305, 1992
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