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Xanthogranulomatous Pyelonephritis
Alessandro Furlan, MD; R. Brooke Jeffrey, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • XGP or XGPN
              • Definitions

                • Chronic infection of kidney and surrounding tissues characterized by destruction of renal parenchyma and replacement by lipid-laden macrophages

              IMAGING

              • General Features

                • Fluoroscopic Findings

                  • Ultrasonographic Findings

                    • CT Findings

                      • MR Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Natural History & Prognosis

                                          • Treatment

                                            DIAGNOSTIC CHECKLIST

                                            • Consider

                                              • Image Interpretation Pearls

                                                Selected References

                                                1. Conti VS et al: Xanthogranulomatous pyelonephritis: the case of a perplexing kidney. BMJ Case Rep. 2014, 2014
                                                2. Craig WD et al: Pyelonephritis: radiologic-pathologic review. Radiographics. 28(1):255-77; quiz 327-8, 2008
                                                3. Bhatt S et al: Renal pseudotumors. AJR Am J Roentgenol. 188(5):1380-7, 2007
                                                4. Loffroy R et al: Xanthogranulomatous pyelonephritis in adults: clinical and radiological findings in diffuse and focal forms. Clin Radiol. 62(9):884-90, 2007
                                                5. Kim J: Ultrasonographic features of focal xanthogranulomatous pyelonephritis. J Ultrasound Med. 23(3):409-16, 2004
                                                6. Cakmakci H et al: Pediatric focal xanthogranulomatous pyelonephritis: dynamic contrast-enhanced MRI findings. Clin Imaging. 26(3):183-6, 2002
                                                7. Kim JC: US and CT findings of xanthogranulomatous pyelonephritis. Clin Imaging. 25(2):118-21, 2001
                                                8. Tiu CM et al: Sonographic features of xanthogranulomatous pyelonephritis. J Clin Ultrasound. 29(5):279-85, 2001
                                                9. Pickhardt PJ et al: From the archives of the AFIP. Infiltrative renal lesions: radiologic-pathologic correlation. Armed Forces Institute of Pathology. Radiographics. 20(1):215-43, 2000
                                                10. Verswijvel G et al: Xanthogranulomatous pyelonephritis: MRI findings in the diffuse and the focal type. Eur Radiol. 10(4):586-9, 2000
                                                11. Fan CM et al: Xanthogranulomatous pyelonephritis. AJR Am J Roentgenol. 165(4):1008, 1995
                                                12. Eastham J et al: Xanthogranulomatous pyelonephritis: clinical findings and surgical considerations. Urology. 43(3):295-9, 1994
                                                13. Rabushka LS et al: Pictorial review: computed tomography of renal inflammatory disease. Urology. 44(4):473-80, 1994
                                                14. Chuang CK et al: Xanthogranulomatous pyelonephritis: experience in 36 cases. J Urol. 147(2):333-6, 1992
                                                15. Hayes WS et al: From the Archives of the AFIP. Xanthogranulomatous pyelonephritis. Radiographics. 11(3):485-98, 1991
                                                16. Mulopulos GP et al: MR imaging of xanthogranulomatous pyelonephritis. J Comput Assist Tomogr. 10(1):154-6, 1986
                                                17. Goldman SM et al: CT of xanthogranulomatous pyelonephritis: radiologic-pathologic correlation. AJR Am J Roentgenol. 142(5):963-9, 1984
                                                18. Bissada NK et al: Preoperative diagnosis of xanthogranulomatous pyelonephritis. Urology. 7(2):228-30, 1976
                                                19. Cha EM et al: Xanthogranulomatous pyelonephritis. Angiographic evaluation. Urology. 3(2):159-62, 1974
                                                20. Vinik M et al: Xanthogranulomatous pyelonephritis: angiographic considerations. Radiology. 92(3):537-40, 1969
                                                21. Iannacone R et al: Bilateral xanthogranulomatous pyelonephritis (XGP) with perirenal extension: MRI findings.  http://www.eurorad.org/case.php?id=2802. Published March 1, 2004. Accessed May 11, 2014
                                                Related Anatomy
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                                                Related Differential Diagnoses
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                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Top Differential Diagnoses

                                                      • Pathology

                                                        • Clinical Issues

                                                          • Diagnostic Checklist

                                                            TERMINOLOGY

                                                            • Abbreviations

                                                              • XGP or XGPN
                                                            • Definitions

                                                              • Chronic infection of kidney and surrounding tissues characterized by destruction of renal parenchyma and replacement by lipid-laden macrophages

                                                            IMAGING

                                                            • General Features

                                                              • Fluoroscopic Findings

                                                                • Ultrasonographic Findings

                                                                  • CT Findings

                                                                    • MR Findings

                                                                      • Imaging Recommendations

                                                                        DIFFERENTIAL DIAGNOSIS

                                                                          PATHOLOGY

                                                                          • General Features

                                                                            • Staging, Grading, & Classification

                                                                              • Gross Pathologic & Surgical Features

                                                                                • Microscopic Features

                                                                                  CLINICAL ISSUES

                                                                                  • Presentation

                                                                                    • Demographics

                                                                                      • Natural History & Prognosis

                                                                                        • Treatment

                                                                                          DIAGNOSTIC CHECKLIST

                                                                                          • Consider

                                                                                            • Image Interpretation Pearls

                                                                                              Selected References

                                                                                              1. Conti VS et al: Xanthogranulomatous pyelonephritis: the case of a perplexing kidney. BMJ Case Rep. 2014, 2014
                                                                                              2. Craig WD et al: Pyelonephritis: radiologic-pathologic review. Radiographics. 28(1):255-77; quiz 327-8, 2008
                                                                                              3. Bhatt S et al: Renal pseudotumors. AJR Am J Roentgenol. 188(5):1380-7, 2007
                                                                                              4. Loffroy R et al: Xanthogranulomatous pyelonephritis in adults: clinical and radiological findings in diffuse and focal forms. Clin Radiol. 62(9):884-90, 2007
                                                                                              5. Kim J: Ultrasonographic features of focal xanthogranulomatous pyelonephritis. J Ultrasound Med. 23(3):409-16, 2004
                                                                                              6. Cakmakci H et al: Pediatric focal xanthogranulomatous pyelonephritis: dynamic contrast-enhanced MRI findings. Clin Imaging. 26(3):183-6, 2002
                                                                                              7. Kim JC: US and CT findings of xanthogranulomatous pyelonephritis. Clin Imaging. 25(2):118-21, 2001
                                                                                              8. Tiu CM et al: Sonographic features of xanthogranulomatous pyelonephritis. J Clin Ultrasound. 29(5):279-85, 2001
                                                                                              9. Pickhardt PJ et al: From the archives of the AFIP. Infiltrative renal lesions: radiologic-pathologic correlation. Armed Forces Institute of Pathology. Radiographics. 20(1):215-43, 2000
                                                                                              10. Verswijvel G et al: Xanthogranulomatous pyelonephritis: MRI findings in the diffuse and the focal type. Eur Radiol. 10(4):586-9, 2000
                                                                                              11. Fan CM et al: Xanthogranulomatous pyelonephritis. AJR Am J Roentgenol. 165(4):1008, 1995
                                                                                              12. Eastham J et al: Xanthogranulomatous pyelonephritis: clinical findings and surgical considerations. Urology. 43(3):295-9, 1994
                                                                                              13. Rabushka LS et al: Pictorial review: computed tomography of renal inflammatory disease. Urology. 44(4):473-80, 1994
                                                                                              14. Chuang CK et al: Xanthogranulomatous pyelonephritis: experience in 36 cases. J Urol. 147(2):333-6, 1992
                                                                                              15. Hayes WS et al: From the Archives of the AFIP. Xanthogranulomatous pyelonephritis. Radiographics. 11(3):485-98, 1991
                                                                                              16. Mulopulos GP et al: MR imaging of xanthogranulomatous pyelonephritis. J Comput Assist Tomogr. 10(1):154-6, 1986
                                                                                              17. Goldman SM et al: CT of xanthogranulomatous pyelonephritis: radiologic-pathologic correlation. AJR Am J Roentgenol. 142(5):963-9, 1984
                                                                                              18. Bissada NK et al: Preoperative diagnosis of xanthogranulomatous pyelonephritis. Urology. 7(2):228-30, 1976
                                                                                              19. Cha EM et al: Xanthogranulomatous pyelonephritis. Angiographic evaluation. Urology. 3(2):159-62, 1974
                                                                                              20. Vinik M et al: Xanthogranulomatous pyelonephritis: angiographic considerations. Radiology. 92(3):537-40, 1969
                                                                                              21. Iannacone R et al: Bilateral xanthogranulomatous pyelonephritis (XGP) with perirenal extension: MRI findings.  http://www.eurorad.org/case.php?id=2802. Published March 1, 2004. Accessed May 11, 2014