link
Bookmarks
Zollinger-Ellison Syndrome
Michael P. Federle, MD, FACR
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Log inSubscribe
0
4
1
4

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Zollinger-Ellison syndrome (ZES)
            • Definitions

              • Severe peptic ulcer disease associated with marked ↑ in gastric acid due to gastrin-producing endocrine tumor (gastrinoma) of pancreas

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Angiographic Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Epelboym I et al: Zollinger-Ellison syndrome: classical considerations and current controversies. Oncologist. 19(1):44-50, 2014
                                              2. Krampitz GW et al: Current management of the Zollinger-Ellison syndrome. Adv Surg. 47:59-79, 2013
                                              3. Metz DC et al: Gastrointestinal neuroendocrine tumors: pancreatic endocrine tumors. Gastroenterology. 135(5):1469-92, 2008
                                              4. Klose KJ et al: Localisation and staging of gastrin producing tumours using cross-sectional imaging modalities. Wien Klin Wochenschr. 119(19-20):588-92, 2007
                                              5. Levy AD et al: From the archives of the AFIP: Gastrointestinal carcinoids: imaging features with clinicopathologic comparison. Radiographics. 27(1):237-57, 2007
                                              6. Levy AD et al: Duodenal carcinoids: imaging features with clinical-pathologic comparison. Radiology. 237(3):967-72, 2005
                                              7. Pfannenberg AC et al: Dual-phase multidetector thin-section CT in detecting duodenal gastrinoma. Abdom Imaging. 30(5):543-7, 2005
                                              8. Nino-Murcia M et al: Multidetector-row CT and volumetric imaging of pancreatic neoplasms. Gastroenterol Clin North Am. 31(3):881-96, 2002
                                              9. Oshikawa O et al: Dynamic sonography of pancreatic tumors: comparison with dynamic CT. AJR Am J Roentgenol. 178(5):1133-7, 2002
                                              10. Rodallec M et al: Helical CT of pancreatic endocrine tumors. J Comput Assist Tomogr. 26(5):728-33, 2002
                                              11. Sheth S et al: Helical CT of islet cell tumors of the pancreas: typical and atypical manifestations. AJR Am J Roentgenol. 179(3):725-30, 2002
                                              12. Sheth S et al: Imaging of uncommon tumors of the pancreas. Radiol Clin North Am. 40(6):1273-87, vi, 2002
                                              13. Fidler JL et al: Imaging of neuroendocrine tumors of the pancreas. Int J Gastrointest Cancer. 30(1-2):73-85, 2001
                                              14. Ichikawa T et al: Islet cell tumor of the pancreas: biphasic CT versus MR imaging in tumor detection. Radiology. 216(1):163-71, 2000
                                              15. Buetow PC et al: Islet cell tumors of the pancreas: clinical, radiologic, and pathologic correlation in diagnosis and localization. Radiographics. 17(2):453-72; quiz 472A-472B, 1997
                                              Related Anatomy
                                              Loading...
                                              Related Differential Diagnoses
                                              Loading...
                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Clinical Issues

                                                        TERMINOLOGY

                                                        • Abbreviations

                                                          • Zollinger-Ellison syndrome (ZES)
                                                        • Definitions

                                                          • Severe peptic ulcer disease associated with marked ↑ in gastric acid due to gastrin-producing endocrine tumor (gastrinoma) of pancreas

                                                        IMAGING

                                                        • General Features

                                                          • Radiographic Findings

                                                            • CT Findings

                                                              • MR Findings

                                                                • Ultrasonographic Findings

                                                                  • Angiographic Findings

                                                                    • Imaging Recommendations

                                                                      DIFFERENTIAL DIAGNOSIS

                                                                        PATHOLOGY

                                                                        • General Features

                                                                          • Gross Pathologic & Surgical Features

                                                                            • Microscopic Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Consider

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Epelboym I et al: Zollinger-Ellison syndrome: classical considerations and current controversies. Oncologist. 19(1):44-50, 2014
                                                                                          2. Krampitz GW et al: Current management of the Zollinger-Ellison syndrome. Adv Surg. 47:59-79, 2013
                                                                                          3. Metz DC et al: Gastrointestinal neuroendocrine tumors: pancreatic endocrine tumors. Gastroenterology. 135(5):1469-92, 2008
                                                                                          4. Klose KJ et al: Localisation and staging of gastrin producing tumours using cross-sectional imaging modalities. Wien Klin Wochenschr. 119(19-20):588-92, 2007
                                                                                          5. Levy AD et al: From the archives of the AFIP: Gastrointestinal carcinoids: imaging features with clinicopathologic comparison. Radiographics. 27(1):237-57, 2007
                                                                                          6. Levy AD et al: Duodenal carcinoids: imaging features with clinical-pathologic comparison. Radiology. 237(3):967-72, 2005
                                                                                          7. Pfannenberg AC et al: Dual-phase multidetector thin-section CT in detecting duodenal gastrinoma. Abdom Imaging. 30(5):543-7, 2005
                                                                                          8. Nino-Murcia M et al: Multidetector-row CT and volumetric imaging of pancreatic neoplasms. Gastroenterol Clin North Am. 31(3):881-96, 2002
                                                                                          9. Oshikawa O et al: Dynamic sonography of pancreatic tumors: comparison with dynamic CT. AJR Am J Roentgenol. 178(5):1133-7, 2002
                                                                                          10. Rodallec M et al: Helical CT of pancreatic endocrine tumors. J Comput Assist Tomogr. 26(5):728-33, 2002
                                                                                          11. Sheth S et al: Helical CT of islet cell tumors of the pancreas: typical and atypical manifestations. AJR Am J Roentgenol. 179(3):725-30, 2002
                                                                                          12. Sheth S et al: Imaging of uncommon tumors of the pancreas. Radiol Clin North Am. 40(6):1273-87, vi, 2002
                                                                                          13. Fidler JL et al: Imaging of neuroendocrine tumors of the pancreas. Int J Gastrointest Cancer. 30(1-2):73-85, 2001
                                                                                          14. Ichikawa T et al: Islet cell tumor of the pancreas: biphasic CT versus MR imaging in tumor detection. Radiology. 216(1):163-71, 2000
                                                                                          15. Buetow PC et al: Islet cell tumors of the pancreas: clinical, radiologic, and pathologic correlation in diagnosis and localization. Radiographics. 17(2):453-72; quiz 472A-472B, 1997